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Blast cells present

MedGen UID:
98109
•Concept ID:
C0427540
•
Finding
Synonym: Blast Cells Present
SNOMED CT: Blast cells present (165547005)

Definition

A laboratory test result indicating the presence of blast cells in a blood sample. [from NCI]

Professional guidelines

PubMed

A pilot study of monoclonal antibody targeted radiotherapy in the treatment of central nervous system leukaemia in children.
Pizer B, Papanastassiou V, Hancock J, Cassano W, Coakham H, Kemshead J
Br J Haematol 1991 Apr;77(4):466-72. doi: 10.1111/j.1365-2141.1991.tb08611.x. PMID: 2025571

Recent clinical studies

Etiology

Criteria for defining a complete remission in acute myeloid leukaemia revisited. An analysis of patients treated in HOVON-SAKK co-operative group studies.
de Greef GE, van Putten WL, Boogaerts M, Huijgens PC, Verdonck LF, Vellenga E, Theobald M, Jacky E, Löwenberg B; Dutch-Belgian Hemato-Oncology Co-operative Group HOVON; Swiss Group for Clinical Cancer Research SAKK
Br J Haematol 2005 Jan;128(2):184-91. doi: 10.1111/j.1365-2141.2004.05285.x. PMID: 15638852

Diagnosis

Transient abnormal myelopoiesis in a phenotypically normal newborn with polyclonal trisomy 21.
Corazza F, Astolfi A, Libri V, Franzoni M, Serravalle S, Alessandroni R, Melchionda F, Pession A
Int J Hematol 2014 Jun;99(6):794-7. Epub 2014 Apr 26 doi: 10.1007/s12185-014-1584-0. PMID: 24771229
Bcl-2, cell cycle regulatory proteins and corticosensitivity in childhood acute lymphoblastic leukaemia.
Baghdassarian N, Bertrand Y, Gerland LM, Ffrench P, Duhaut P, Bryon PA, Magaud JP, Ffrench M
Leuk Lymphoma 2001 Sep-Oct;42(5):1067-75. doi: 10.3109/10428190109097727. PMID: 11697624
Acute lymphoid leukemias following either a previous chronic myelogenous leukemia or myelodysplastic syndrome: phenotypic and genomic differences.
Hernández JM, Sánchez I, González M, Orfao A, González-Sarmiento R, San Miguel JF
Am J Hematol 1993 Aug;43(4):256-8. doi: 10.1002/ajh.2830430405. PMID: 8396849
Generation of a sheep x mouse heterohybridoma cell line (1C6.3a6T.1D7) and evaluation of its use in the production of ovine monoclonal antibodies.
Flynn JN, Harkiss GD, Hopkins J
J Immunol Methods 1989 Jul 26;121(2):237-46. doi: 10.1016/0022-1759(89)90166-x. PMID: 2760466
Human acute myelomonocytic leukemia: serologic studies with simian antisera.
Mohanakumar T, Miller DS, Metzgar RS
Blood 1976 Sep;48(3):339-50. PMID: 1066171

Therapy

Criteria for defining a complete remission in acute myeloid leukaemia revisited. An analysis of patients treated in HOVON-SAKK co-operative group studies.
de Greef GE, van Putten WL, Boogaerts M, Huijgens PC, Verdonck LF, Vellenga E, Theobald M, Jacky E, Löwenberg B; Dutch-Belgian Hemato-Oncology Co-operative Group HOVON; Swiss Group for Clinical Cancer Research SAKK
Br J Haematol 2005 Jan;128(2):184-91. doi: 10.1111/j.1365-2141.2004.05285.x. PMID: 15638852
Bcl-2, cell cycle regulatory proteins and corticosensitivity in childhood acute lymphoblastic leukaemia.
Baghdassarian N, Bertrand Y, Gerland LM, Ffrench P, Duhaut P, Bryon PA, Magaud JP, Ffrench M
Leuk Lymphoma 2001 Sep-Oct;42(5):1067-75. doi: 10.3109/10428190109097727. PMID: 11697624
A pilot study of monoclonal antibody targeted radiotherapy in the treatment of central nervous system leukaemia in children.
Pizer B, Papanastassiou V, Hancock J, Cassano W, Coakham H, Kemshead J
Br J Haematol 1991 Apr;77(4):466-72. doi: 10.1111/j.1365-2141.1991.tb08611.x. PMID: 2025571
Pharmacokinetics of daunorubicin as a determinant of response in acute myeloid leukemia.
Kokenberg E, van der Steuijt K, Löwenberg B, Nooter K, Sonneveld P
Haematol Blood Transfus 1987;30:283-7. doi: 10.1007/978-3-642-71213-5_42. PMID: 3476358

Prognosis

Bcl-2, cell cycle regulatory proteins and corticosensitivity in childhood acute lymphoblastic leukaemia.
Baghdassarian N, Bertrand Y, Gerland LM, Ffrench P, Duhaut P, Bryon PA, Magaud JP, Ffrench M
Leuk Lymphoma 2001 Sep-Oct;42(5):1067-75. doi: 10.3109/10428190109097727. PMID: 11697624
Correlations between the clinical course, characteristics of blast cells, and karyotype patterns in chronic myeloid leukemia.
Fleischman EW, Prigogina EL, Volkova MA, Frenkel MA, Zakhartchenko NA, Konstantinova LN, Puchkova GP, Balakirev SA
Hum Genet 1981;58(3):285-93. doi: 10.1007/BF00294925. PMID: 6948765
Human acute myelomonocytic leukemia: serologic studies with simian antisera.
Mohanakumar T, Miller DS, Metzgar RS
Blood 1976 Sep;48(3):339-50. PMID: 1066171

Clinical prediction guides

Bcl-2, cell cycle regulatory proteins and corticosensitivity in childhood acute lymphoblastic leukaemia.
Baghdassarian N, Bertrand Y, Gerland LM, Ffrench P, Duhaut P, Bryon PA, Magaud JP, Ffrench M
Leuk Lymphoma 2001 Sep-Oct;42(5):1067-75. doi: 10.3109/10428190109097727. PMID: 11697624
Pharmacokinetics of daunorubicin as a determinant of response in acute myeloid leukemia.
Kokenberg E, van der Steuijt K, Löwenberg B, Nooter K, Sonneveld P
Haematol Blood Transfus 1987;30:283-7. doi: 10.1007/978-3-642-71213-5_42. PMID: 3476358

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