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Carcinoma in situ of appendix

MedGen UID:
83853
Concept ID:
C0347125
Neoplastic Process
Synonyms: carcinoma in situ of appendix; carcinoma in situ of the appendix; carcinoma in situ of vermiform appendix; stage 0 appendix cancer; stage 0 appendix carcinoma; stage 0 appendix carcinoma aJCC v7; stage 0 vermiform appendix carcinoma; vermiform appendix carcinoma in situ; vermiform appendix in situ carcinoma
SNOMED CT: Carcinoma in situ of appendix (92539008)
 
Monarch Initiative: MONDO:0021290

Definition

A in situ carcinoma that involves the vermiform appendix. [from MONDO]

Professional guidelines

PubMed

Coates AS, Winer EP, Goldhirsch A, Gelber RD, Gnant M, Piccart-Gebhart M, Thürlimann B, Senn HJ; Panel Members
Ann Oncol 2015 Aug;26(8):1533-46. Epub 2015 May 4 doi: 10.1093/annonc/mdv221. PMID: 25939896Free PMC Article
Trimble CL, Method M, Leitao M, Lu K, Ioffe O, Hampton M, Higgins R, Zaino R, Mutter GL; Society of Gynecologic Oncology Clinical Practice Committee
Obstet Gynecol 2012 Nov;120(5):1160-75. doi: 10.1097/aog.0b013e31826bb121. PMID: 23090535Free PMC Article
Levine M, Moutquin JM, Walton R, Feightner J; Canadian Task Force on Preventive Health Care and the Canadian Breast Cancer Initiative's Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer
CMAJ 2001 Jun 12;164(12):1681-90. PMID: 11450210Free PMC Article

Recent clinical studies

Etiology

Akita M, Yanagimoto H, Tsugawa D, Ajiki T, Masuda A, Komatsu M, Goto T, Kido M, Toyama H, Fukumoto T
Clin J Gastroenterol 2023 Jun;16(3):476-481. Epub 2023 Mar 3 doi: 10.1007/s12328-023-01778-x. PMID: 36867354
Kunkiel M, Niwińska A
Sci Rep 2021 Nov 22;11(1):22645. doi: 10.1038/s41598-021-02126-0. PMID: 34811426Free PMC Article
Coates AS, Winer EP, Goldhirsch A, Gelber RD, Gnant M, Piccart-Gebhart M, Thürlimann B, Senn HJ; Panel Members
Ann Oncol 2015 Aug;26(8):1533-46. Epub 2015 May 4 doi: 10.1093/annonc/mdv221. PMID: 25939896Free PMC Article
Levine M, Moutquin JM, Walton R, Feightner J; Canadian Task Force on Preventive Health Care and the Canadian Breast Cancer Initiative's Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer
CMAJ 2001 Jun 12;164(12):1681-90. PMID: 11450210Free PMC Article
Prat J
Adv Anat Pathol 1999 Sep;6(5):247-74. doi: 10.1097/00125480-199909000-00002. PMID: 10472378

Diagnosis

Kunkiel M, Niwińska A
Sci Rep 2021 Nov 22;11(1):22645. doi: 10.1038/s41598-021-02126-0. PMID: 34811426Free PMC Article
Bennett C, Green S, DeCaestecker J, Almond M, Barr H, Bhandari P, Ragunath K, Singh R, Jankowski J
Cochrane Database Syst Rev 2020 May 22;5(5):CD007334. doi: 10.1002/14651858.CD007334.pub5. PMID: 32442322Free PMC Article
Bennett C, Green S, Decaestecker J, Almond M, Barr H, Bhandari P, Ragunath K, Singh R, Jankowski J
Cochrane Database Syst Rev 2012 Nov 14;11:CD007334. doi: 10.1002/14651858.CD007334.pub4. PMID: 23152243
Trimble CL, Method M, Leitao M, Lu K, Ioffe O, Hampton M, Higgins R, Zaino R, Mutter GL; Society of Gynecologic Oncology Clinical Practice Committee
Obstet Gynecol 2012 Nov;120(5):1160-75. doi: 10.1097/aog.0b013e31826bb121. PMID: 23090535Free PMC Article
Am J Clin Pathol 1995 Dec;104(6):614-9. doi: 10.1093/ajcp/104.6.614. PMID: 8526202

Therapy

Bennett C, Green S, DeCaestecker J, Almond M, Barr H, Bhandari P, Ragunath K, Singh R, Jankowski J
Cochrane Database Syst Rev 2020 May 22;5(5):CD007334. doi: 10.1002/14651858.CD007334.pub5. PMID: 32442322Free PMC Article
Coates AS, Winer EP, Goldhirsch A, Gelber RD, Gnant M, Piccart-Gebhart M, Thürlimann B, Senn HJ; Panel Members
Ann Oncol 2015 Aug;26(8):1533-46. Epub 2015 May 4 doi: 10.1093/annonc/mdv221. PMID: 25939896Free PMC Article
Bennett C, Green S, Decaestecker J, Almond M, Barr H, Bhandari P, Ragunath K, Singh R, Jankowski J
Cochrane Database Syst Rev 2012 Nov 14;11:CD007334. doi: 10.1002/14651858.CD007334.pub4. PMID: 23152243
Bennett C, Green S, Barr H, Bhandari P, Decaestecker J, Ragunath K, Singh R, Tawil A, Jankowski J
Cochrane Database Syst Rev 2010 May 12;(5):CD007334. doi: 10.1002/14651858.CD007334.pub3. PMID: 20464752
Levine M, Moutquin JM, Walton R, Feightner J; Canadian Task Force on Preventive Health Care and the Canadian Breast Cancer Initiative's Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer
CMAJ 2001 Jun 12;164(12):1681-90. PMID: 11450210Free PMC Article

Prognosis

Kunkiel M, Niwińska A
Sci Rep 2021 Nov 22;11(1):22645. doi: 10.1038/s41598-021-02126-0. PMID: 34811426Free PMC Article
Coates AS, Winer EP, Goldhirsch A, Gelber RD, Gnant M, Piccart-Gebhart M, Thürlimann B, Senn HJ; Panel Members
Ann Oncol 2015 Aug;26(8):1533-46. Epub 2015 May 4 doi: 10.1093/annonc/mdv221. PMID: 25939896Free PMC Article
Trimble CL, Method M, Leitao M, Lu K, Ioffe O, Hampton M, Higgins R, Zaino R, Mutter GL; Society of Gynecologic Oncology Clinical Practice Committee
Obstet Gynecol 2012 Nov;120(5):1160-75. doi: 10.1097/aog.0b013e31826bb121. PMID: 23090535Free PMC Article
Lee KR, Scully RE
Am J Surg Pathol 2000 Nov;24(11):1447-64. doi: 10.1097/00000478-200011000-00001. PMID: 11075847
Prat J
Adv Anat Pathol 1999 Sep;6(5):247-74. doi: 10.1097/00125480-199909000-00002. PMID: 10472378

Clinical prediction guides

Akita M, Yanagimoto H, Tsugawa D, Ajiki T, Masuda A, Komatsu M, Goto T, Kido M, Toyama H, Fukumoto T
Clin J Gastroenterol 2023 Jun;16(3):476-481. Epub 2023 Mar 3 doi: 10.1007/s12328-023-01778-x. PMID: 36867354
Kunkiel M, Niwińska A
Sci Rep 2021 Nov 22;11(1):22645. doi: 10.1038/s41598-021-02126-0. PMID: 34811426Free PMC Article
Trimble CL, Method M, Leitao M, Lu K, Ioffe O, Hampton M, Higgins R, Zaino R, Mutter GL; Society of Gynecologic Oncology Clinical Practice Committee
Obstet Gynecol 2012 Nov;120(5):1160-75. doi: 10.1097/aog.0b013e31826bb121. PMID: 23090535Free PMC Article
O'Connell JT, Tomlinson JS, Roberts AA, McGonigle KF, Barsky SH
Am J Pathol 2002 Aug;161(2):551-64. doi: 10.1016/S0002-9440(10)64211-3. PMID: 12163380Free PMC Article
Corfitsen MT, Pedersen IR, Lebech AM, Kaae HH
Acta Obstet Gynecol Scand 1991;70(7-8):601-4. doi: 10.3109/00016349109007924. PMID: 1785278

Recent systematic reviews

Bennett C, Green S, DeCaestecker J, Almond M, Barr H, Bhandari P, Ragunath K, Singh R, Jankowski J
Cochrane Database Syst Rev 2020 May 22;5(5):CD007334. doi: 10.1002/14651858.CD007334.pub5. PMID: 32442322Free PMC Article
Bennett C, Green S, Decaestecker J, Almond M, Barr H, Bhandari P, Ragunath K, Singh R, Jankowski J
Cochrane Database Syst Rev 2012 Nov 14;11:CD007334. doi: 10.1002/14651858.CD007334.pub4. PMID: 23152243
Bennett C, Green S, Barr H, Bhandari P, Decaestecker J, Ragunath K, Singh R, Tawil A, Jankowski J
Cochrane Database Syst Rev 2010 May 12;(5):CD007334. doi: 10.1002/14651858.CD007334.pub3. PMID: 20464752
Green S, Tawil A, Barr H, Bennett C, Bhandari P, Decaestecker J, Ragunath K, Singh R, Jankowski J
Cochrane Database Syst Rev 2009 Apr 15;(2):CD007334. doi: 10.1002/14651858.CD007334.pub2. PMID: 19370683
Levine M, Moutquin JM, Walton R, Feightner J; Canadian Task Force on Preventive Health Care and the Canadian Breast Cancer Initiative's Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer
CMAJ 2001 Jun 12;164(12):1681-90. PMID: 11450210Free PMC Article

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