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Delayed skeletal maturation

MedGen UID:
505344
Concept ID:
CN002495
Finding
Synonyms: Delayed bone age; Delayed bone age before puberty; Delayed bone maturation; Delayed skeletal development; Retarded bone age; Skeletal maturation retardation
 

Definition

A decreased rate of skeletal maturation. Delayed skeletal maturation can be diagnosed on the basis of an estimation of the bone age from radiographs of specific bones in the human body. [from HPO]

Recent clinical studies

Etiology

Cohen A, Addonizio LJ, Softness B, Lamour JM, McMahon DJ, Addesso V, Diamond BE, Shane E
Pediatr Transplant 2004 Apr;8(2):126-35. doi: 10.1046/j.1399-3046.2003.00123.x. PMID: 15049792
Rovner AJ, Schall JI, Jawad AF, Piccoli DA, Stallings VA, Mulberg AE, Zemel BS
J Pediatr Gastroenterol Nutr 2002 Oct;35(4):495-502. PMID: 12394373
Allen DB, Julius JR, Breen TJ, Attie KM
J Clin Endocrinol Metab 1998 Aug;83(8):2824-9. doi: 10.1210/jcem.83.8.5036. PMID: 9709954
Singhal A, Davies P, Wierenga KJ, Thomas P, Serjeant G
Am J Clin Nutr 1997 Aug;66(2):386-90. PMID: 9250118
Kristmundsdottir F, Burwell RG, Harrison MH
Acta Orthop Scand 1987 Jun;58(3):277-9. PMID: 3630662

Diagnosis

Abanto J, Celiberti P, Alves FB, Rossier V, Vieira SA, Ciamponi AL, Raggio DP
J Dent Child (Chic) 2010 Jan-Apr;77(1):54-8. PMID: 20359431
Suarez EA, d'Alva CB, Campbell A, Miller-Horn J, Dever M, Faerber E, Medonca BB, Latronico AC, De Luca F
J Pediatr Endocrinol Metab 2007 Aug;20(8):923-31. PMID: 17937064
Cohen A, Addonizio LJ, Softness B, Lamour JM, McMahon DJ, Addesso V, Diamond BE, Shane E
Pediatr Transplant 2004 Apr;8(2):126-35. doi: 10.1046/j.1399-3046.2003.00123.x. PMID: 15049792
Paesano PL, Vigone MC, Siragusa V, Chiumello G, Del Maschio A, Mora S
Pediatr Radiol 1998 Aug;28(8):622-6. doi: 10.1007/s002470050432. PMID: 9716638
Kristmundsdottir F, Burwell RG, Harrison MH
Acta Orthop Scand 1987 Jun;58(3):277-9. PMID: 3630662

Therapy

Rovner AJ, Schall JI, Jawad AF, Piccoli DA, Stallings VA, Mulberg AE, Zemel BS
J Pediatr Gastroenterol Nutr 2002 Oct;35(4):495-502. PMID: 12394373
Allen DB, Julius JR, Breen TJ, Attie KM
J Clin Endocrinol Metab 1998 Aug;83(8):2824-9. doi: 10.1210/jcem.83.8.5036. PMID: 9709954
Roberts CD, Vogtle L, Stevenson RD
J Pediatr 1994 Nov;125(5 Pt 1):824-8. PMID: 7965443
Allen DB
J Pediatr 1993 Jan;122(1):32-6. PMID: 8419612
Kleiger B, Resnick MI
Bull Hosp Joint Dis 1966 Oct;27(2):90-5. PMID: 5972636

Prognosis

Heuschkel R, Salvestrini C, Beattie RM, Hildebrand H, Walters T, Griffiths A
Inflamm Bowel Dis 2008 Jun;14(6):839-49. doi: 10.1002/ibd.20378. PMID: 18266237
Cohen A, Addonizio LJ, Softness B, Lamour JM, McMahon DJ, Addesso V, Diamond BE, Shane E
Pediatr Transplant 2004 Apr;8(2):126-35. doi: 10.1046/j.1399-3046.2003.00123.x. PMID: 15049792
Svedström E, Parto K, Marttinen M, Virtama P, Simell O
Skeletal Radiol 1993;22(1):11-6. PMID: 8430340
Kristmundsdottir F, Burwell RG, Harrison MH
Acta Orthop Scand 1987 Jun;58(3):277-9. PMID: 3630662
Shore RM, Chesney RW, Mazess RB, Rose PG, Bargman GJ
Calcif Tissue Int 1982;34(6):519-22. PMID: 6819070

Clinical prediction guides

Bruckner AL, Bedocs LA, Keiser E, Tang JY, Doernbrack C, Arbuckle HA, Berman S, Kent K, Bachrach LK
J Am Acad Dermatol 2011 Nov;65(5):1001-9. Epub 2011 May 7 doi: 10.1016/j.jaad.2010.08.028. [Epub ahead of print] PMID: 21550693
Cohen A, Addonizio LJ, Softness B, Lamour JM, McMahon DJ, Addesso V, Diamond BE, Shane E
Pediatr Transplant 2004 Apr;8(2):126-35. doi: 10.1046/j.1399-3046.2003.00123.x. PMID: 15049792
Wasserstein MP, Larkin AE, Glass RB, Schuchman EH, Desnick RJ, McGovern MM
J Pediatr 2003 Apr;142(4):424-8. doi: 10.1067/mpd.2003.113. PMID: 12712061
Rovner AJ, Schall JI, Jawad AF, Piccoli DA, Stallings VA, Mulberg AE, Zemel BS
J Pediatr Gastroenterol Nutr 2002 Oct;35(4):495-502. PMID: 12394373
Kristmundsdottir F, Burwell RG, Harrison MH
Acta Orthop Scand 1987 Jun;58(3):277-9. PMID: 3630662

Recent systematic reviews

Heuschkel R, Salvestrini C, Beattie RM, Hildebrand H, Walters T, Griffiths A
Inflamm Bowel Dis 2008 Jun;14(6):839-49. doi: 10.1002/ibd.20378. PMID: 18266237

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