U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

First trimester bleeding

MedGen UID:
406618
•Concept ID:
C1880779
•
Pathologic Function
Synonym: First Trimester Bleeding
SNOMED CT: First trimester bleeding (1323351000000104)

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFirst trimester bleeding

Professional guidelines

PubMed

First Trimester Bleeding: Evaluation and Management.
Hendriks E, MacNaughton H, MacKenzie MC
Am Fam Physician 2019 Feb 1;99(3):166-174. PMID: 30702252
Clinical diagnosis and treatment of ectopic pregnancy.
Alkatout I, Honemeyer U, Strauss A, Tinelli A, Malvasi A, Jonat W, Mettler L, Schollmeyer T
Obstet Gynecol Surv 2013 Aug;68(8):571-81. doi: 10.1097/OGX.0b013e31829cdbeb. PMID: 23921671
Midwifery management of first trimester bleeding and early pregnancy loss.
Thorstensen KA
J Midwifery Womens Health 2000 Nov-Dec;45(6):481-97. doi: 10.1016/s1526-9523(00)00071-4. PMID: 11151462

Recent clinical studies

Etiology

Early pregnancy loss.
Jackson T, Watkins E
JAAPA 2021 Mar 1;34(3):22-27. doi: 10.1097/01.JAA.0000733216.66078.ac. PMID: 33528169
Association Between First-Trimester Bleeding and Retained Placenta Requiring Dilatation and Curettage.
Le Gallee M, Lee S, Spence AR, Czuzoj-Shulman N, Klam S, Abenhaim HA
J Obstet Gynaecol Can 2021 Apr;43(4):463-468. Epub 2020 Aug 25 doi: 10.1016/j.jogc.2020.07.012. PMID: 33153944
First Trimester Bleeding: Evaluation and Management.
Hendriks E, MacNaughton H, MacKenzie MC
Am Fam Physician 2019 Feb 1;99(3):166-174. PMID: 30702252
First trimester bleeding.
Deutchman M, Tubay AT, Turok D
Am Fam Physician 2009 Jun 1;79(11):985-94. PMID: 19514696
First trimester bleeding evaluation.
Dogra V, Paspulati RM, Bhatt S
Ultrasound Q 2005 Jun;21(2):69-85; quiz 149-50, 153-4. PMID: 15905817

Diagnosis

Common Issues in Prenatal Care: First Trimester Bleeding.
Sundermeyer RL, LeFevre N, Kolker A, Williamson B
FP Essent 2023 Feb;525:7-12. PMID: 36780553
First Trimester Bleeding: Evaluation and Management.
Hendriks E, MacNaughton H, MacKenzie MC
Am Fam Physician 2019 Feb 1;99(3):166-174. PMID: 30702252
First trimester bleeding.
Deutchman M, Tubay AT, Turok D
Am Fam Physician 2009 Jun 1;79(11):985-94. PMID: 19514696
Sonography in first trimester bleeding.
Dighe M, Cuevas C, Moshiri M, Dubinsky T, Dogra VS
J Clin Ultrasound 2008 Jul-Aug;36(6):352-66. doi: 10.1002/jcu.20451. PMID: 18335508
First trimester bleeding evaluation.
Dogra V, Paspulati RM, Bhatt S
Ultrasound Q 2005 Jun;21(2):69-85; quiz 149-50, 153-4. PMID: 15905817

Therapy

Common Issues in Prenatal Care: First Trimester Bleeding.
Sundermeyer RL, LeFevre N, Kolker A, Williamson B
FP Essent 2023 Feb;525:7-12. PMID: 36780553
Association Between First-Trimester Bleeding and Retained Placenta Requiring Dilatation and Curettage.
Le Gallee M, Lee S, Spence AR, Czuzoj-Shulman N, Klam S, Abenhaim HA
J Obstet Gynaecol Can 2021 Apr;43(4):463-468. Epub 2020 Aug 25 doi: 10.1016/j.jogc.2020.07.012. PMID: 33153944
Fetal Growth Patterns in Pregnancies With First-Trimester Bleeding.
Bever AM, Pugh SJ, Kim S, Newman RB, Grobman WA, Chien EK, Wing DA, Li H, Albert PS, Grantz KL
Obstet Gynecol 2018 Jun;131(6):1021-1030. doi: 10.1097/AOG.0000000000002616. PMID: 29742672Free PMC Article
First-trimester bleeding and twin pregnancy outcomes after in vitro fertilization.
Eaton JL, Zhang X, Kazer RR
Fertil Steril 2016 Jul;106(1):140-143. Epub 2016 Apr 7 doi: 10.1016/j.fertnstert.2016.03.027. PMID: 27060729
First trimester bleeding.
Deutchman M, Tubay AT, Turok D
Am Fam Physician 2009 Jun 1;79(11):985-94. PMID: 19514696

Prognosis

Retrospective Study of First Trimester Metrorrhagia: Pregnancy Follow-Up and Relationship with the Appearance of Gestational Complications.
Baños Cándenas L, Abehsera Davó D, Castaño Frías L, González Mesa E
Medicina (Kaunas) 2023 Jul 27;59(8) doi: 10.3390/medicina59081370. PMID: 37629660Free PMC Article
Common Issues in Prenatal Care: First Trimester Bleeding.
Sundermeyer RL, LeFevre N, Kolker A, Williamson B
FP Essent 2023 Feb;525:7-12. PMID: 36780553
Patterns and predictors of vaginal bleeding in the first trimester of pregnancy.
Hasan R, Baird DD, Herring AH, Olshan AF, Jonsson Funk ML, Hartmann KE
Ann Epidemiol 2010 Jul;20(7):524-31. doi: 10.1016/j.annepidem.2010.02.006. PMID: 20538195Free PMC Article
First trimester bleeding evaluation.
Dogra V, Paspulati RM, Bhatt S
Ultrasound Q 2005 Jun;21(2):69-85; quiz 149-50, 153-4. PMID: 15905817
Midwifery management of first trimester bleeding and early pregnancy loss.
Thorstensen KA
J Midwifery Womens Health 2000 Nov-Dec;45(6):481-97. doi: 10.1016/s1526-9523(00)00071-4. PMID: 11151462

Clinical prediction guides

Fetal Growth Patterns in Pregnancies With First-Trimester Bleeding.
Bever AM, Pugh SJ, Kim S, Newman RB, Grobman WA, Chien EK, Wing DA, Li H, Albert PS, Grantz KL
Obstet Gynecol 2018 Jun;131(6):1021-1030. doi: 10.1097/AOG.0000000000002616. PMID: 29742672Free PMC Article
Patterns and predictors of vaginal bleeding in the first trimester of pregnancy.
Hasan R, Baird DD, Herring AH, Olshan AF, Jonsson Funk ML, Hartmann KE
Ann Epidemiol 2010 Jul;20(7):524-31. doi: 10.1016/j.annepidem.2010.02.006. PMID: 20538195Free PMC Article
Maternal and perinatal outcome in women with threatened miscarriage in the first trimester: a systematic review.
Saraswat L, Bhattacharya S, Maheshwari A, Bhattacharya S
BJOG 2010 Feb;117(3):245-57. Epub 2009 Nov 26 doi: 10.1111/j.1471-0528.2009.02427.x. PMID: 19943827
Association between first-trimester vaginal bleeding and miscarriage.
Hasan R, Baird DD, Herring AH, Olshan AF, Jonsson Funk ML, Hartmann KE
Obstet Gynecol 2009 Oct;114(4):860-867. doi: 10.1097/AOG.0b013e3181b79796. PMID: 19888046Free PMC Article
First trimester bleeding evaluation.
Dogra V, Paspulati RM, Bhatt S
Ultrasound Q 2005 Jun;21(2):69-85; quiz 149-50, 153-4. PMID: 15905817

Recent systematic reviews

Outcome of cesarean scar pregnancy according to gestational age at diagnosis: A systematic review and meta-analysis.
Timor-Tritsch I, Buca D, Di Mascio D, Cali G, D'Amico A, Monteagudo A, Tinari S, Morlando M, Nappi L, Greco P, Rizzo G, Liberati M, Jose-Palacios-Jaraquemada, D'Antonio F
Eur J Obstet Gynecol Reprod Biol 2021 Mar;258:53-59. Epub 2020 Nov 12 doi: 10.1016/j.ejogrb.2020.11.036. PMID: 33421811
Maternal and perinatal outcome in women with threatened miscarriage in the first trimester: a systematic review.
Saraswat L, Bhattacharya S, Maheshwari A, Bhattacharya S
BJOG 2010 Feb;117(3):245-57. Epub 2009 Nov 26 doi: 10.1111/j.1471-0528.2009.02427.x. PMID: 19943827

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...