Display Settings:

Format

Send to:

Choose Destination

Sudden cardiac death(SCD)

MedGen UID:
38841
Concept ID:
C0085298
Pathologic Function
Synonyms: SCD; Sudden adult death syndrome; sudden cardiac arrest
SNOMED CT: Sudden cardiac death (95281009)
 
OMIM®: 115080

Definition

Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005) [from MeSH]

Recent clinical studies

Etiology

Varvarigou V, Farioli A, Korre M, Sato S, Dahabreh IJ, Kales SN
BMJ 2014 Nov 18;349:g6534. PMID: 25406189Free PMC Article
Plourde B, Sarrazin JF, Nault I, Poirier P
Expert Rev Cardiovasc Ther 2014 Sep;12(9):1099-110. doi: 10.1586/14779072.2014.952283. PMID: 25160995
Stojanovska J, Garg A, Patel S, Melville DM, Kazerooni EA, Mueller GC
Radiographics 2013 Nov-Dec;33(7):1977-2001. doi: 10.1148/rg.337125073. PMID: 24224591
Friedman AN, Yu Z, Tabbey R, Denski C, Tamez H, Wenger J, Thadhani R, Li Y, Watkins BA
Kidney Int 2013 Jun;83(6):1130-5. Epub 2013 Feb 6 doi: 10.1038/ki.2013.4. [Epub ahead of print] PMID: 23389417Free PMC Article
Pilmer CM, Porter B, Kirsh JA, Hicks AL, Gledhill N, Jamnik V, Faught BE, Hildebrandt D, McCartney N, Gow RM, Goodman J, Krahn AD
Heart Rhythm 2013 Apr;10(4):517-23. Epub 2012 Dec 8 doi: 10.1016/j.hrthm.2012.12.003. [Epub ahead of print] PMID: 23232084

Diagnosis

Varvarigou V, Farioli A, Korre M, Sato S, Dahabreh IJ, Kales SN
BMJ 2014 Nov 18;349:g6534. PMID: 25406189Free PMC Article
Niemeijer MN, van den Berg ME, Eijgelsheim M, van Herpen G, Stricker BH, Kors JA, Rijnbeek PR
Heart 2014 Dec;100(23):1831-6. Epub 2014 Aug 4 doi: 10.1136/heartjnl-2014-305671. [Epub ahead of print] PMID: 25092875
Goldstein BA, Chang TI, Mitani AA, Assimes TL, Winkelmayer WC
Clin J Am Soc Nephrol 2014 Jan;9(1):82-91. Epub 2013 Oct 31 doi: 10.2215/CJN.03050313. [Epub ahead of print] PMID: 24178968Free PMC Article
Stojanovska J, Garg A, Patel S, Melville DM, Kazerooni EA, Mueller GC
Radiographics 2013 Nov-Dec;33(7):1977-2001. doi: 10.1148/rg.337125073. PMID: 24224591
Sarquella-Brugada G, Campuzano O, Iglesias A, Sánchez-Malagón J, Guerra-Balic M, Brugada J, Brugada R
Cardiol Young 2013 Apr;23(2):159-73. Epub 2012 Jul 24 doi: 10.1017/S1047951112001138. [Epub ahead of print] PMID: 22824130

Therapy

Fishbein DP, Hellkamp AS, Mark DB, Walsh MN, Poole JE, Anderson J, Johnson G, Lee KL, Bardy GH; SCD-HeFT Investigators
J Am Coll Cardiol 2014 Jun 17;63(23):2560-8. Epub 2014 Apr 9 doi: 10.1016/j.jacc.2014.02.602. [Epub ahead of print] PMID: 24727258
Goldstein BA, Chang TI, Mitani AA, Assimes TL, Winkelmayer WC
Clin J Am Soc Nephrol 2014 Jan;9(1):82-91. Epub 2013 Oct 31 doi: 10.2215/CJN.03050313. [Epub ahead of print] PMID: 24178968Free PMC Article
Makki N, Swaminathan PD, Hanmer J, Olshansky B
Europace 2014 Jan;16(1):55-62. Epub 2013 Sep 20 doi: 10.1093/europace/eut277. [Epub ahead of print] PMID: 24058182
Al Chekakie MO
J Cardiovasc Pharmacol Ther 2013 Sep;18(5):412-26. Epub 2013 Jun 13 doi: 10.1177/1074248413491496. [Epub ahead of print] PMID: 23766358
Friedman AN, Yu Z, Tabbey R, Denski C, Tamez H, Wenger J, Thadhani R, Li Y, Watkins BA
Kidney Int 2013 Jun;83(6):1130-5. Epub 2013 Feb 6 doi: 10.1038/ki.2013.4. [Epub ahead of print] PMID: 23389417Free PMC Article

Prognosis

Niemeijer MN, van den Berg ME, Eijgelsheim M, van Herpen G, Stricker BH, Kors JA, Rijnbeek PR
Heart 2014 Dec;100(23):1831-6. Epub 2014 Aug 4 doi: 10.1136/heartjnl-2014-305671. [Epub ahead of print] PMID: 25092875
Fishbein DP, Hellkamp AS, Mark DB, Walsh MN, Poole JE, Anderson J, Johnson G, Lee KL, Bardy GH; SCD-HeFT Investigators
J Am Coll Cardiol 2014 Jun 17;63(23):2560-8. Epub 2014 Apr 9 doi: 10.1016/j.jacc.2014.02.602. [Epub ahead of print] PMID: 24727258
Stojanovska J, Garg A, Patel S, Melville DM, Kazerooni EA, Mueller GC
Radiographics 2013 Nov-Dec;33(7):1977-2001. doi: 10.1148/rg.337125073. PMID: 24224591
Al Chekakie MO
J Cardiovasc Pharmacol Ther 2013 Sep;18(5):412-26. Epub 2013 Jun 13 doi: 10.1177/1074248413491496. [Epub ahead of print] PMID: 23766358
Pilmer CM, Porter B, Kirsh JA, Hicks AL, Gledhill N, Jamnik V, Faught BE, Hildebrandt D, McCartney N, Gow RM, Goodman J, Krahn AD
Heart Rhythm 2013 Apr;10(4):517-23. Epub 2012 Dec 8 doi: 10.1016/j.hrthm.2012.12.003. [Epub ahead of print] PMID: 23232084

Clinical prediction guides

Varvarigou V, Farioli A, Korre M, Sato S, Dahabreh IJ, Kales SN
BMJ 2014 Nov 18;349:g6534. PMID: 25406189Free PMC Article
Niemeijer MN, van den Berg ME, Eijgelsheim M, van Herpen G, Stricker BH, Kors JA, Rijnbeek PR
Heart 2014 Dec;100(23):1831-6. Epub 2014 Aug 4 doi: 10.1136/heartjnl-2014-305671. [Epub ahead of print] PMID: 25092875
Goldstein BA, Chang TI, Mitani AA, Assimes TL, Winkelmayer WC
Clin J Am Soc Nephrol 2014 Jan;9(1):82-91. Epub 2013 Oct 31 doi: 10.2215/CJN.03050313. [Epub ahead of print] PMID: 24178968Free PMC Article
Makki N, Swaminathan PD, Hanmer J, Olshansky B
Europace 2014 Jan;16(1):55-62. Epub 2013 Sep 20 doi: 10.1093/europace/eut277. [Epub ahead of print] PMID: 24058182
Angelini P, Vidovich MI, Lawless CE, Elayda MA, Lopez JA, Wolf D, Willerson JT
Tex Heart Inst J 2013;40(2):148-55. PMID: 23678212Free PMC Article

Recent systematic reviews

Niemeijer MN, van den Berg ME, Eijgelsheim M, van Herpen G, Stricker BH, Kors JA, Rijnbeek PR
Heart 2014 Dec;100(23):1831-6. Epub 2014 Aug 4 doi: 10.1136/heartjnl-2014-305671. [Epub ahead of print] PMID: 25092875
Vasiliadis I, Kolovou G, Mavrogeni S, Nair DR, Mikhailidis DP
J Diabetes Complications 2014 Jul-Aug;28(4):573-9. Epub 2014 Feb 18 doi: 10.1016/j.jdiacomp.2014.02.003. [Epub ahead of print] PMID: 24666923
Makki N, Swaminathan PD, Hanmer J, Olshansky B
Europace 2014 Jan;16(1):55-62. Epub 2013 Sep 20 doi: 10.1093/europace/eut277. [Epub ahead of print] PMID: 24058182
Proclemer A, Lewalter T, Bongiorni MG, Svendsen JH, Pison L, Lundqvist CB; Scientific Initiative Committee, European Heart Rhythm Association
Europace 2013 Jul;15(7):1059-62. doi: 10.1093/europace/eut187. PMID: 23794672
Angelini P, Vidovich MI, Lawless CE, Elayda MA, Lopez JA, Wolf D, Willerson JT
Tex Heart Inst J 2013;40(2):148-55. PMID: 23678212Free PMC Article

Supplemental Content

Table of contents

    Consumer resources

    Medical Encyclopedia

    Outreach and support

    PubMed Health

    Clinical Trials

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...