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Intracranial Aneurysm

MedGen UID:
2960
•Concept ID:
C0007766
•
Disease or Syndrome
Synonyms: Aneurysm, Intracranial; Aneurysms, Intracranial; Intracranial Aneurysms
SNOMED CT: Intracranial aneurysm (128609009)

Definition

A congenital or acquired aneurysm within the cranium. [from NCI]

Professional guidelines

PubMed

2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid Hemorrhage: A Guideline From the American Heart Association/American Stroke Association.
Hoh BL, Ko NU, Amin-Hanjani S, Chou SH-Y, Cruz-Flores S, Dangayach NS, Derdeyn CP, Du R, Hänggi D, Hetts SW, Ifejika NL, Johnson R, Keigher KM, Leslie-Mazwi TM, Lucke-Wold B, Rabinstein AA, Robicsek SA, Stapleton CJ, Suarez JI, Tjoumakaris SI, Welch BG
Stroke 2023 Jul;54(7):e314-e370. Epub 2023 May 22 doi: 10.1161/STR.0000000000000436. PMID: 37212182
Diagnosis and Treatment of Unruptured Intracranial Aneurysms and Aneurysmal Subarachnoid Hemorrhage.
Tawk RG, Hasan TF, D'Souza CE, Peel JB, Freeman WD
Mayo Clin Proc 2021 Jul;96(7):1970-2000. Epub 2021 May 13 doi: 10.1016/j.mayocp.2021.01.005. PMID: 33992453
Unruptured intracranial aneurysms: epidemiology, natural history, management options, and familial screening.
Brown RD Jr, Broderick JP
Lancet Neurol 2014 Apr;13(4):393-404. doi: 10.1016/S1474-4422(14)70015-8. PMID: 24646873

Recent clinical studies

Etiology

Intracranial Vascular Procedures.
Gross WL, Sacho RH
Anesthesiol Clin 2021 Mar;39(1):1-18. Epub 2021 Jan 9 doi: 10.1016/j.anclin.2020.10.001. PMID: 33563374
Headache and Aneurysm.
Kwon OK
Neuroimaging Clin N Am 2019 May;29(2):255-260. Epub 2019 Feb 20 doi: 10.1016/j.nic.2019.01.004. PMID: 30926115
Unruptured intracranial aneurysms: development, rupture and preventive management.
Etminan N, Rinkel GJ
Nat Rev Neurol 2016 Dec;12(12):699-713. Epub 2016 Nov 3 doi: 10.1038/nrneurol.2016.150. PMID: 27808265
Unruptured Cerebral Aneurysms: Evaluation and Management.
Ajiboye N, Chalouhi N, Starke RM, Zanaty M, Bell R
ScientificWorldJournal 2015;2015:954954. Epub 2015 Jun 4 doi: 10.1155/2015/954954. PMID: 26146657Free PMC Article
Unruptured intracranial aneurysms: epidemiology, natural history, management options, and familial screening.
Brown RD Jr, Broderick JP
Lancet Neurol 2014 Apr;13(4):393-404. doi: 10.1016/S1474-4422(14)70015-8. PMID: 24646873

Diagnosis

Artificial Intelligence Applications in Intracranial Aneurysm: Achievements, Challenges and Opportunities.
Alwalid O, Long X, Xie M, Han P
Acad Radiol 2022 Mar;29 Suppl 3:S201-S214. Epub 2021 Aug 8 doi: 10.1016/j.acra.2021.06.013. PMID: 34376335
Headache and Aneurysm.
Kwon OK
Neuroimaging Clin N Am 2019 May;29(2):255-260. Epub 2019 Feb 20 doi: 10.1016/j.nic.2019.01.004. PMID: 30926115
Unruptured Cerebral Aneurysms: Evaluation and Management.
Ajiboye N, Chalouhi N, Starke RM, Zanaty M, Bell R
ScientificWorldJournal 2015;2015:954954. Epub 2015 Jun 4 doi: 10.1155/2015/954954. PMID: 26146657Free PMC Article
Mouse models of intracranial aneurysm.
Wang Y, Emeto TI, Lee J, Marshman L, Moran C, Seto SW, Golledge J
Brain Pathol 2015 May;25(3):237-47. Epub 2014 Oct 30 doi: 10.1111/bpa.12175. PMID: 25041057Free PMC Article
Unruptured intracranial aneurysms: epidemiology, natural history, management options, and familial screening.
Brown RD Jr, Broderick JP
Lancet Neurol 2014 Apr;13(4):393-404. doi: 10.1016/S1474-4422(14)70015-8. PMID: 24646873

Therapy

Treatments for unruptured intracranial aneurysms.
Pontes FGB, da Silva EM, Baptista-Silva JC, Vasconcelos V
Cochrane Database Syst Rev 2021 May 10;5(5):CD013312. doi: 10.1002/14651858.CD013312.pub2. PMID: 33971026Free PMC Article
Unruptured Intracranial Aneurysms- Pathogenesis and Individualized Management.
Etminan N, Dörfler A, Steinmetz H
Dtsch Arztebl Int 2020 Apr 3;117(14):235-242. doi: 10.3238/arztebl.2020.0235. PMID: 32449895Free PMC Article
SCENT Trial.
Meyers PM, Coon AL, Kan PT, Wakhloo AK, Hanel RA
Stroke 2019 Jun;50(6):1473-1479. Epub 2019 May 14 doi: 10.1161/STROKEAHA.118.024135. PMID: 31084335
Cerebrovascular neurosurgery 2014.
Salem M, Gross BA, Du R, Thomas AJ
J Clin Neurosci 2015 May;22(5):775-8. Epub 2015 Feb 15 doi: 10.1016/j.jocn.2015.01.002. PMID: 25691077
International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion.
Molyneux AJ, Kerr RS, Yu LM, Clarke M, Sneade M, Yarnold JA, Sandercock P; International Subarachnoid Aneurysm Trial (ISAT) Collaborative Group
Lancet 2005 Sep 3-9;366(9488):809-17. doi: 10.1016/S0140-6736(05)67214-5. PMID: 16139655

Prognosis

Outcomes Associated With Intracranial Aneurysm Treatments Reported as Safe, Effective, or Durable: A Systematic Review and Meta-Analysis.
Volovici V, Verploegh IS, Satoer D, Vrancken Peeters NJMC, Sadigh Y, Vergouwen MDI, Schouten JW, Bruggeman G, Pisica D, Yildirim G, Cozar A, Muller F, Zidaru AM, Gori K, Tzourmpaki N, Schnell E, Thioub M, Kicielinski K, van Doormaal PJ, Velinov N, Boutarbouch M, Lawton MT, Lanzino G, Amin-Hanjani S, Dammers R, Meling TR
JAMA Netw Open 2023 Sep 5;6(9):e2331798. doi: 10.1001/jamanetworkopen.2023.31798. PMID: 37656458Free PMC Article
Formation of intracranial de novo aneurysms and recurrence after neck clipping: a systematic review and meta-analysis.
Spiessberger A, Vogt DR, Fandino J, Marbacher S
J Neurosurg 2019 Feb 22;132(2):456-464. doi: 10.3171/2018.10.JNS181281. PMID: 30797217
Intraprocedural Rupture During Endovascular Treatment of Intracranial Aneurysm: Clinical Results and Literature Review.
Park YK, Yi HJ, Choi KS, Lee YJ, Chun HJ
World Neurosurg 2018 Jun;114:e605-e615. Epub 2018 Mar 14 doi: 10.1016/j.wneu.2018.03.040. PMID: 29548958
European Stroke Organization guidelines for the management of intracranial aneurysms and subarachnoid haemorrhage.
Steiner T, Juvela S, Unterberg A, Jung C, Forsting M, Rinkel G; European Stroke Organization
Cerebrovasc Dis 2013;35(2):93-112. Epub 2013 Feb 7 doi: 10.1159/000346087. PMID: 23406828
International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion.
Molyneux AJ, Kerr RS, Yu LM, Clarke M, Sneade M, Yarnold JA, Sandercock P; International Subarachnoid Aneurysm Trial (ISAT) Collaborative Group
Lancet 2005 Sep 3-9;366(9488):809-17. doi: 10.1016/S0140-6736(05)67214-5. PMID: 16139655

Clinical prediction guides

Correlation of intracranial and aortic aneurysms: current trends and evidence.
Moughal S, Bashir M
Asian Cardiovasc Thorac Ann 2020 Jun;28(5):250-257. Epub 2020 Jun 2 doi: 10.1177/0218492320930848. PMID: 32486829
Prediction of Unruptured Intracranial Aneurysm Evolution: The UCAN Project.
L'Allinec V, Chatel S, Karakachoff M, Bourcereau E, Lamoureux Z, Gaignard A, Autrusseau F, Jouan S, Vion AC, Loirand G, Desal H, Naggara O, Redon R, Edjlali M, Bourcier R
Neurosurgery 2020 Jul 1;87(1):150-156. doi: 10.1093/neuros/nyaa093. PMID: 32374868
Cerebral Aneurysm Size before and after Rupture: Case Series and Literature Review.
Yi J, Zielinski D, Chen M
J Stroke Cerebrovasc Dis 2016 May;25(5):1244-1248. Epub 2016 Feb 27 doi: 10.1016/j.jstrokecerebrovasdis.2016.01.031. PMID: 26935121
Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: a pooled analysis of six prospective cohort studies.
Greving JP, Wermer MJ, Brown RD Jr, Morita A, Juvela S, Yonekura M, Ishibashi T, Torner JC, Nakayama T, Rinkel GJ, Algra A
Lancet Neurol 2014 Jan;13(1):59-66. Epub 2013 Nov 27 doi: 10.1016/S1474-4422(13)70263-1. PMID: 24290159
European Stroke Organization guidelines for the management of intracranial aneurysms and subarachnoid haemorrhage.
Steiner T, Juvela S, Unterberg A, Jung C, Forsting M, Rinkel G; European Stroke Organization
Cerebrovasc Dis 2013;35(2):93-112. Epub 2013 Feb 7 doi: 10.1159/000346087. PMID: 23406828

Recent systematic reviews

Treatments for unruptured intracranial aneurysms.
Pontes FGB, da Silva EM, Baptista-Silva JC, Vasconcelos V
Cochrane Database Syst Rev 2021 May 10;5(5):CD013312. doi: 10.1002/14651858.CD013312.pub2. PMID: 33971026Free PMC Article
Worldwide Incidence of Aneurysmal Subarachnoid Hemorrhage According to Region, Time Period, Blood Pressure, and Smoking Prevalence in the Population: A Systematic Review and Meta-analysis.
Etminan N, Chang HS, Hackenberg K, de Rooij NK, Vergouwen MDI, Rinkel GJE, Algra A
JAMA Neurol 2019 May 1;76(5):588-597. doi: 10.1001/jamaneurol.2019.0006. PMID: 30659573Free PMC Article
Endovascular treatment of cerebral aneurysms using flow-diverter devices: A systematic review.
Briganti F, Leone G, Marseglia M, Mariniello G, Caranci F, Brunetti A, Maiuri F
Neuroradiol J 2015 Aug;28(4):365-75. Epub 2015 Aug 27 doi: 10.1177/1971400915602803. PMID: 26314872Free PMC Article
Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: a pooled analysis of six prospective cohort studies.
Greving JP, Wermer MJ, Brown RD Jr, Morita A, Juvela S, Yonekura M, Ishibashi T, Torner JC, Nakayama T, Rinkel GJ, Algra A
Lancet Neurol 2014 Jan;13(1):59-66. Epub 2013 Nov 27 doi: 10.1016/S1474-4422(13)70263-1. PMID: 24290159
Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis.
Vlak MH, Algra A, Brandenburg R, Rinkel GJ
Lancet Neurol 2011 Jul;10(7):626-36. doi: 10.1016/S1474-4422(11)70109-0. PMID: 21641282

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