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Grade 5 Hemorrhage and Bleeding, CTCAE Associated with Surgery, CTCAE

MedGen UID:
291728
•Concept ID:
C1556650
•
Finding
Synonym: CTCAE Grade 5 Hemorrhage/bleeding associated with surgery, intra-operative or postoperative

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 5 Hemorrhage and Bleeding, CTCAE Associated with Surgery, CTCAE

Recent clinical studies

Etiology

30-day morbidity and mortality after transoral robotic surgery for human papillomavirus (HPV) associated oropharyngeal squamous cell carcinoma: A retrospective analysis of two prospective adjuvant de-escalation trials (MC1273 & MC1675).
Haller TJ, Yin XL, O'Byrne TJ, Moore EJ, Ma DJ, Price KP, Patel SH, Hinni ML, Neben-Wittich MA, McGee LA, Price DL, Janus JR, Kasperbauer JK, Nagel TH, Routman DM, Lester SC, Rwigema JCM, Chintakuntlawar AV, Savvides PS, Garcia JJ, Foote RL, Van Abel KM
Oral Oncol 2023 Feb;137:106248. Epub 2023 Jan 3 doi: 10.1016/j.oraloncology.2022.106248. PMID: 36603364
Patient-oriented toxicity endpoints after head and neck reirradiation with intensity modulated radiation therapy.
Margalit DN, Schoenfeld JD, Rawal B, Haddad RI, Catalano PJ, Goguen LA, Chau NG, Rabinowits G, Lorch JH, Annino DJ, Tishler RB
Oral Oncol 2017 Oct;73:160-165. Epub 2017 Sep 8 doi: 10.1016/j.oraloncology.2017.08.012. PMID: 28939070
Volume-staged radiosurgery for large arteriovenous malformations: an evolving paradigm.
Seymour ZA, Sneed PK, Gupta N, Lawton MT, Molinaro AM, Young W, Dowd CF, Halbach VV, Higashida RT, McDermott MW
J Neurosurg 2016 Jan;124(1):163-74. Epub 2015 Jul 3 doi: 10.3171/2014.12.JNS141308. PMID: 26140495
Hematuria following stereotactic body radiation therapy (SBRT) for clinically localized prostate cancer.
Gurka MK, Chen LN, Bhagat A, Moures R, Kim JS, Yung T, Lei S, Collins BT, Krishnan P, Suy S, Dritschilo A, Lynch JH, Collins SP
Radiat Oncol 2015 Feb 19;10:44. doi: 10.1186/s13014-015-0351-6. PMID: 25890265Free PMC Article
Incidence of bleeding after 15,181 percutaneous biopsies and the role of aspirin.
Atwell TD, Smith RL, Hesley GK, Callstrom MR, Schleck CD, Harmsen WS, Charboneau JW, Welch TJ
AJR Am J Roentgenol 2010 Mar;194(3):784-9. doi: 10.2214/AJR.08.2122. PMID: 20173160

Diagnosis

Gastroduodenal complications after concurrent chemoradiation therapy in patients with hepatocellular carcinoma: endoscopic findings and risk factors.
Chon YE, Seong J, Kim BK, Cha J, Kim SU, Park JY, Ahn SH, Han KH, Chon CY, Shin SK, Kim DY
Int J Radiat Oncol Biol Phys 2011 Dec 1;81(5):1343-51. Epub 2010 Oct 8 doi: 10.1016/j.ijrobp.2010.07.1986. PMID: 20934268

Therapy

30-day morbidity and mortality after transoral robotic surgery for human papillomavirus (HPV) associated oropharyngeal squamous cell carcinoma: A retrospective analysis of two prospective adjuvant de-escalation trials (MC1273 & MC1675).
Haller TJ, Yin XL, O'Byrne TJ, Moore EJ, Ma DJ, Price KP, Patel SH, Hinni ML, Neben-Wittich MA, McGee LA, Price DL, Janus JR, Kasperbauer JK, Nagel TH, Routman DM, Lester SC, Rwigema JCM, Chintakuntlawar AV, Savvides PS, Garcia JJ, Foote RL, Van Abel KM
Oral Oncol 2023 Feb;137:106248. Epub 2023 Jan 3 doi: 10.1016/j.oraloncology.2022.106248. PMID: 36603364
Reproducible safety and efficacy of atezolizumab plus bevacizumab for HCC in clinical practice: Results of the AB-real study.
Fulgenzi CAM, Cheon J, D'Alessio A, Nishida N, Ang C, Marron TU, Wu L, Saeed A, Wietharn B, Cammarota A, Pressiani T, Personeni N, Pinter M, Scheiner B, Balcar L, Napolitano A, Huang YH, Phen S, Naqash AR, Vivaldi C, Salani F, Masi G, Bettinger D, Vogel A, Schönlein M, von Felden J, Schulze K, Wege H, Galle PR, Kudo M, Rimassa L, Singal AG, Sharma R, Cortellini A, Gaillard VE, Chon HJ, Pinato DJ
Eur J Cancer 2022 Nov;175:204-213. Epub 2022 Sep 20 doi: 10.1016/j.ejca.2022.08.024. PMID: 36148739
Patient-oriented toxicity endpoints after head and neck reirradiation with intensity modulated radiation therapy.
Margalit DN, Schoenfeld JD, Rawal B, Haddad RI, Catalano PJ, Goguen LA, Chau NG, Rabinowits G, Lorch JH, Annino DJ, Tishler RB
Oral Oncol 2017 Oct;73:160-165. Epub 2017 Sep 8 doi: 10.1016/j.oraloncology.2017.08.012. PMID: 28939070
Hematuria following stereotactic body radiation therapy (SBRT) for clinically localized prostate cancer.
Gurka MK, Chen LN, Bhagat A, Moures R, Kim JS, Yung T, Lei S, Collins BT, Krishnan P, Suy S, Dritschilo A, Lynch JH, Collins SP
Radiat Oncol 2015 Feb 19;10:44. doi: 10.1186/s13014-015-0351-6. PMID: 25890265Free PMC Article
Incidence of bleeding after 15,181 percutaneous biopsies and the role of aspirin.
Atwell TD, Smith RL, Hesley GK, Callstrom MR, Schleck CD, Harmsen WS, Charboneau JW, Welch TJ
AJR Am J Roentgenol 2010 Mar;194(3):784-9. doi: 10.2214/AJR.08.2122. PMID: 20173160

Prognosis

Reproducible safety and efficacy of atezolizumab plus bevacizumab for HCC in clinical practice: Results of the AB-real study.
Fulgenzi CAM, Cheon J, D'Alessio A, Nishida N, Ang C, Marron TU, Wu L, Saeed A, Wietharn B, Cammarota A, Pressiani T, Personeni N, Pinter M, Scheiner B, Balcar L, Napolitano A, Huang YH, Phen S, Naqash AR, Vivaldi C, Salani F, Masi G, Bettinger D, Vogel A, Schönlein M, von Felden J, Schulze K, Wege H, Galle PR, Kudo M, Rimassa L, Singal AG, Sharma R, Cortellini A, Gaillard VE, Chon HJ, Pinato DJ
Eur J Cancer 2022 Nov;175:204-213. Epub 2022 Sep 20 doi: 10.1016/j.ejca.2022.08.024. PMID: 36148739
Patient-oriented toxicity endpoints after head and neck reirradiation with intensity modulated radiation therapy.
Margalit DN, Schoenfeld JD, Rawal B, Haddad RI, Catalano PJ, Goguen LA, Chau NG, Rabinowits G, Lorch JH, Annino DJ, Tishler RB
Oral Oncol 2017 Oct;73:160-165. Epub 2017 Sep 8 doi: 10.1016/j.oraloncology.2017.08.012. PMID: 28939070
Volume-staged radiosurgery for large arteriovenous malformations: an evolving paradigm.
Seymour ZA, Sneed PK, Gupta N, Lawton MT, Molinaro AM, Young W, Dowd CF, Halbach VV, Higashida RT, McDermott MW
J Neurosurg 2016 Jan;124(1):163-74. Epub 2015 Jul 3 doi: 10.3171/2014.12.JNS141308. PMID: 26140495
Hematuria following stereotactic body radiation therapy (SBRT) for clinically localized prostate cancer.
Gurka MK, Chen LN, Bhagat A, Moures R, Kim JS, Yung T, Lei S, Collins BT, Krishnan P, Suy S, Dritschilo A, Lynch JH, Collins SP
Radiat Oncol 2015 Feb 19;10:44. doi: 10.1186/s13014-015-0351-6. PMID: 25890265Free PMC Article
Incidence of bleeding after 15,181 percutaneous biopsies and the role of aspirin.
Atwell TD, Smith RL, Hesley GK, Callstrom MR, Schleck CD, Harmsen WS, Charboneau JW, Welch TJ
AJR Am J Roentgenol 2010 Mar;194(3):784-9. doi: 10.2214/AJR.08.2122. PMID: 20173160

Clinical prediction guides

Reproducible safety and efficacy of atezolizumab plus bevacizumab for HCC in clinical practice: Results of the AB-real study.
Fulgenzi CAM, Cheon J, D'Alessio A, Nishida N, Ang C, Marron TU, Wu L, Saeed A, Wietharn B, Cammarota A, Pressiani T, Personeni N, Pinter M, Scheiner B, Balcar L, Napolitano A, Huang YH, Phen S, Naqash AR, Vivaldi C, Salani F, Masi G, Bettinger D, Vogel A, Schönlein M, von Felden J, Schulze K, Wege H, Galle PR, Kudo M, Rimassa L, Singal AG, Sharma R, Cortellini A, Gaillard VE, Chon HJ, Pinato DJ
Eur J Cancer 2022 Nov;175:204-213. Epub 2022 Sep 20 doi: 10.1016/j.ejca.2022.08.024. PMID: 36148739
Patient-oriented toxicity endpoints after head and neck reirradiation with intensity modulated radiation therapy.
Margalit DN, Schoenfeld JD, Rawal B, Haddad RI, Catalano PJ, Goguen LA, Chau NG, Rabinowits G, Lorch JH, Annino DJ, Tishler RB
Oral Oncol 2017 Oct;73:160-165. Epub 2017 Sep 8 doi: 10.1016/j.oraloncology.2017.08.012. PMID: 28939070
Volume-staged radiosurgery for large arteriovenous malformations: an evolving paradigm.
Seymour ZA, Sneed PK, Gupta N, Lawton MT, Molinaro AM, Young W, Dowd CF, Halbach VV, Higashida RT, McDermott MW
J Neurosurg 2016 Jan;124(1):163-74. Epub 2015 Jul 3 doi: 10.3171/2014.12.JNS141308. PMID: 26140495
Holmium laser ablation of the prostate (HoLAP): intermediate-term results of 144 patients.
Barski D, Richter M, Winter C, Arsov C, de Geeter P, Rabenalt R, Albers P
World J Urol 2013 Oct;31(5):1253-9. Epub 2012 Jul 11 doi: 10.1007/s00345-012-0901-6. PMID: 22782618
Gastroduodenal complications after concurrent chemoradiation therapy in patients with hepatocellular carcinoma: endoscopic findings and risk factors.
Chon YE, Seong J, Kim BK, Cha J, Kim SU, Park JY, Ahn SH, Han KH, Chon CY, Shin SK, Kim DY
Int J Radiat Oncol Biol Phys 2011 Dec 1;81(5):1343-51. Epub 2010 Oct 8 doi: 10.1016/j.ijrobp.2010.07.1986. PMID: 20934268

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