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Refractory Small Cell Glioblastoma

MedGen UID:
1708479
Concept ID:
C5235850
Neoplastic Process

Definition

A small cell glioblastoma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Small Cell Glioblastoma

Professional guidelines

PubMed

Kim H, Zheng S, Amini SS, Virk SM, Mikkelsen T, Brat DJ, Grimsby J, Sougnez C, Muller F, Hu J, Sloan AE, Cohen ML, Van Meir EG, Scarpace L, Laird PW, Weinstein JN, Lander ES, Gabriel S, Getz G, Meyerson M, Chin L, Barnholtz-Sloan JS, Verhaak RG
Genome Res 2015 Mar;25(3):316-27. Epub 2015 Feb 3 doi: 10.1101/gr.180612.114. PMID: 25650244Free PMC Article
Triscott J, Rose Pambid M, Dunn SE
Stem Cells 2015 Apr;33(4):1042-6. doi: 10.1002/stem.1956. PMID: 25588723
McCubrey JA, Lahair MM, Franklin RA
Mol Pharmacol 2006 Aug;70(2):437-9. Epub 2006 May 4 doi: 10.1124/mol.106.026252. PMID: 16675657

Recent clinical studies

Etiology

Ihata T, Nonoguchi N, Fujishiro T, Omura N, Kawabata S, Kajimoto Y, Wanibuchi M
Photodiagnosis Photodyn Ther 2022 Dec;40:103056. Epub 2022 Aug 6 doi: 10.1016/j.pdpdt.2022.103056. PMID: 35944845
Chen YT, Tsai HP, Wu CC, Chen CY, Chai CY, Kwan AL
Pathol Oncol Res 2019 Jul;25(3):1003-1013. Epub 2018 Jun 9 doi: 10.1007/s12253-018-0422-8. PMID: 29948615
Chinese Journal of Cancer
Chin J Cancer 2017 Mar 27;36(1):33. doi: 10.1186/s40880-017-0200-0. PMID: 28347321Free PMC Article
Drugs R D 2007;8(3):176-87. doi: 10.2165/00126839-200708030-00005. PMID: 17472413
Avramis IA, Christodoulopoulos G, Suzuki A, Laug WE, Gonzalez-Gomez I, McNamara G, Sausville EA, Avramis VI
Cancer Chemother Pharmacol 2002 Dec;50(6):479-89. Epub 2002 Oct 17 doi: 10.1007/s00280-002-0507-6. PMID: 12451475

Diagnosis

Sharif T, Dai C, Martell E, Ghassemi-Rad MS, Hanes MR, Murphy PJ, Kennedy BE, Venugopal C, Subapanditha M, Giacomantonio CA, Marcato P, Singh SK, Gujar S
Clin Cancer Res 2019 Mar 15;25(6):2001-2017. Epub 2018 Dec 28 doi: 10.1158/1078-0432.CCR-17-3177. PMID: 30593514
Garrigue P, Tang J, Ding L, Bouhlel A, Tintaru A, Laurini E, Huang Y, Lyu Z, Zhang M, Fernandez S, Balasse L, Lan W, Mas E, Marson D, Weng Y, Liu X, Giorgio S, Iovanna J, Pricl S, Guillet B, Peng L
Proc Natl Acad Sci U S A 2018 Nov 6;115(45):11454-11459. Epub 2018 Oct 22 doi: 10.1073/pnas.1812938115. PMID: 30348798Free PMC Article
Triscott J, Rose Pambid M, Dunn SE
Stem Cells 2015 Apr;33(4):1042-6. doi: 10.1002/stem.1956. PMID: 25588723
Carrasco-García E, Saceda M, Grasso S, Rocamora-Reverte L, Conde M, Gómez-Martínez A, García-Morales P, Ferragut JA, Martínez-Lacaci I
Exp Cell Res 2011 Jun 10;317(10):1476-89. Epub 2011 Apr 1 doi: 10.1016/j.yexcr.2011.03.015. PMID: 21439954
McCubrey JA, Lahair MM, Franklin RA
Mol Pharmacol 2006 Aug;70(2):437-9. Epub 2006 May 4 doi: 10.1124/mol.106.026252. PMID: 16675657

Therapy

Triscott J, Rose Pambid M, Dunn SE
Stem Cells 2015 Apr;33(4):1042-6. doi: 10.1002/stem.1956. PMID: 25588723
Berezowska S, Schlegel J
Curr Pharm Des 2011;17(23):2468-87. doi: 10.2174/138161211797249233. PMID: 21827413
Loew S, Schmidt U, Unterberg A, Halatsch ME
Anticancer Agents Med Chem 2009 Jul;9(6):703-15. doi: 10.2174/187152009788680019. PMID: 19601750
McCubrey JA, Lahair MM, Franklin RA
Mol Pharmacol 2006 Aug;70(2):437-9. Epub 2006 May 4 doi: 10.1124/mol.106.026252. PMID: 16675657
Scatena R
Expert Opin Investig Drugs 2000 Sep;9(9):2159-65. doi: 10.1517/13543784.9.9.2159. PMID: 11060800

Prognosis

Vengoji R, Ponnusamy MP, Rachagani S, Mahapatra S, Batra SK, Shonka N, Macha MA
Carcinogenesis 2019 Mar 12;40(1):2-14. doi: 10.1093/carcin/bgy171. PMID: 30475990Free PMC Article
Chen YT, Tsai HP, Wu CC, Chen CY, Chai CY, Kwan AL
Pathol Oncol Res 2019 Jul;25(3):1003-1013. Epub 2018 Jun 9 doi: 10.1007/s12253-018-0422-8. PMID: 29948615
Cho YJ, Kang W, Kim SH, Sa JK, Kim N, Paddison PJ, Kim M, Joo KM, Hwang YI, Nam DH
Int J Oncol 2016 Mar;48(3):1053-62. Epub 2016 Jan 11 doi: 10.3892/ijo.2016.3328. PMID: 26783102
Venugopal C, Hallett R, Vora P, Manoranjan B, Mahendram S, Qazi MA, McFarlane N, Subapanditha M, Nolte SM, Singh M, Bakhshinyan D, Garg N, Vijayakumar T, Lach B, Provias JP, Reddy K, Murty NK, Doble BW, Bhatia M, Hassell JA, Singh SK
Clin Cancer Res 2015 Dec 1;21(23):5324-37. Epub 2015 Jul 7 doi: 10.1158/1078-0432.CCR-14-3147. PMID: 26152745
Loew S, Schmidt U, Unterberg A, Halatsch ME
Anticancer Agents Med Chem 2009 Jul;9(6):703-15. doi: 10.2174/187152009788680019. PMID: 19601750

Clinical prediction guides

Moujalled D, Southon AG, Saleh E, Brinkmann K, Ke F, Iliopoulos M, Cross RS, Jenkins MR, Nhu D, Wang Z, Shi MX, Kluck RM, Lessene G, Grabow S, Bush AI, Strasser A
Cell Death Differ 2022 Jul;29(7):1335-1348. Epub 2022 Mar 24 doi: 10.1038/s41418-022-00977-2. PMID: 35332309Free PMC Article
Chinese Journal of Cancer
Chin J Cancer 2017 Mar 27;36(1):33. doi: 10.1186/s40880-017-0200-0. PMID: 28347321Free PMC Article
Kim H, Zheng S, Amini SS, Virk SM, Mikkelsen T, Brat DJ, Grimsby J, Sougnez C, Muller F, Hu J, Sloan AE, Cohen ML, Van Meir EG, Scarpace L, Laird PW, Weinstein JN, Lander ES, Gabriel S, Getz G, Meyerson M, Chin L, Barnholtz-Sloan JS, Verhaak RG
Genome Res 2015 Mar;25(3):316-27. Epub 2015 Feb 3 doi: 10.1101/gr.180612.114. PMID: 25650244Free PMC Article
Yamashita-Kashima Y, Fujimoto-Ouchi K, Yorozu K, Kurasawa M, Yanagisawa M, Yasuno H, Mori K
BMC Cancer 2012 Jan 25;12:37. doi: 10.1186/1471-2407-12-37. PMID: 22273502Free PMC Article
Loew S, Schmidt U, Unterberg A, Halatsch ME
Anticancer Agents Med Chem 2009 Jul;9(6):703-15. doi: 10.2174/187152009788680019. PMID: 19601750

Supplemental Content

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