U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Fredrickson Type I Lipidemia

MedGen UID:
163630
•Concept ID:
C0856526
•
Disease or Syndrome

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFredrickson Type I Lipidemia

Professional guidelines

PubMed

Rosuvastatin for the treatment of hypercholesterolemia.
Culhane NS, Lettieri SL, Skae JR
Pharmacotherapy 2005 Jul;25(7):990-1000. doi: 10.1592/phco.2005.25.7.990. PMID: 16006277
Neonatal diagnosis of Fredrickson type II hyperlipoproteinaemia.
Andersen GE
Postgrad Med J 1975;51(8):suppl 93-4. PMID: 215988
Neonatal diagnosis of familial type-II hyperlipoproteinaemia.
Kwiterovich PO Jr, Levy RI, Fredrickson DS
Lancet 1973 Jan 20;1(7795):118-21. doi: 10.1016/s0140-6736(73)90194-3. PMID: 4118465

Recent clinical studies

Etiology

Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk.
Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Páll D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM; PROMINENT Investigators
N Engl J Med 2022 Nov 24;387(21):1923-1934. Epub 2022 Nov 5 doi: 10.1056/NEJMoa2210645. PMID: 36342113
Dysbetalipoproteinemia: Differentiating Multifactorial Remnant Cholesterol Disease From Genetic ApoE Deficiency.
Paquette M, Bernard S, Paré G, Baass A
J Clin Endocrinol Metab 2022 Jan 18;107(2):538-548. doi: 10.1210/clinem/dgab648. PMID: 34467996
Genetic bases of hypertriglyceridemic phenotypes.
Johansen CT, Hegele RA
Curr Opin Lipidol 2011 Aug;22(4):247-53. doi: 10.1097/MOL.0b013e3283471972. PMID: 21519249
Issues in hyperlipidemic pancreatitis.
Yadav D, Pitchumoni CS
J Clin Gastroenterol 2003 Jan;36(1):54-62. doi: 10.1097/00004836-200301000-00016. PMID: 12488710
Soy and cholesterol reduction: clinical experience.
Sirtori CR, Lovati MR, Manzoni C, Monetti M, Pazzucconi F, Gatti E
J Nutr 1995 Mar;125(3 Suppl):598S-605S. doi: 10.1093/jn/125.suppl_3.598S. PMID: 7884540

Diagnosis

Diagnosis of remnant hyperlipidaemia.
Paquette M, Bernard S, Baass A
Curr Opin Lipidol 2022 Aug 1;33(4):227-230. doi: 10.1097/MOL.0000000000000831. PMID: 35942808
Dysbetalipoproteinemia: an extreme disorder of remnant metabolism.
Marais D
Curr Opin Lipidol 2015 Aug;26(4):292-7. doi: 10.1097/MOL.0000000000000192. PMID: 26103610
Dysbetalipoproteinaemia: a mixed hyperlipidaemia of remnant lipoproteins due to mutations in apolipoprotein E.
Marais AD, Solomon GA, Blom DJ
Crit Rev Clin Lab Sci 2014 Feb;51(1):46-62. Epub 2014 Jan 9 doi: 10.3109/10408363.2013.870526. PMID: 24405372
Genetic bases of hypertriglyceridemic phenotypes.
Johansen CT, Hegele RA
Curr Opin Lipidol 2011 Aug;22(4):247-53. doi: 10.1097/MOL.0b013e3283471972. PMID: 21519249
Issues in hyperlipidemic pancreatitis.
Yadav D, Pitchumoni CS
J Clin Gastroenterol 2003 Jan;36(1):54-62. doi: 10.1097/00004836-200301000-00016. PMID: 12488710

Therapy

Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk.
Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Páll D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM; PROMINENT Investigators
N Engl J Med 2022 Nov 24;387(21):1923-1934. Epub 2022 Nov 5 doi: 10.1056/NEJMoa2210645. PMID: 36342113
Rosuvastatin for the treatment of hypercholesterolemia.
Culhane NS, Lettieri SL, Skae JR
Pharmacotherapy 2005 Jul;25(7):990-1000. doi: 10.1592/phco.2005.25.7.990. PMID: 16006277
High frequency of Fredrickson's phenotypes IV and IIb in Brazilians infected by human immunodeficiency virus.
Albuquerque EM, de Faria EC, Oliveira HC, Magro DO, Castilho LN
BMC Infect Dis 2005 Jun 14;5:47. doi: 10.1186/1471-2334-5-47. PMID: 15955243Free PMC Article
Update on fenofibrate.
Guay DR
Cardiovasc Drug Rev 2002 Winter;20(4):281-302. doi: 10.1111/j.1527-3466.2002.tb00098.x. PMID: 12481201
Soy and cholesterol reduction: clinical experience.
Sirtori CR, Lovati MR, Manzoni C, Monetti M, Pazzucconi F, Gatti E
J Nutr 1995 Mar;125(3 Suppl):598S-605S. doi: 10.1093/jn/125.suppl_3.598S. PMID: 7884540

Prognosis

Dysbetalipoproteinaemia: a mixed hyperlipidaemia of remnant lipoproteins due to mutations in apolipoprotein E.
Marais AD, Solomon GA, Blom DJ
Crit Rev Clin Lab Sci 2014 Feb;51(1):46-62. Epub 2014 Jan 9 doi: 10.3109/10408363.2013.870526. PMID: 24405372
Extracorporeal LDL cholesterol elimination (25 years of experience in CZ).
Blaha M, Zadak Z, Blaha V, Andrys C, Havel E, Vyroubal P, Blazek M, Filip S, Lanska M, Maly J
Atheroscler Suppl 2009 Dec 29;10(5):17-20. doi: 10.1016/S1567-5688(09)71804-5. PMID: 20129368
Issues in hyperlipidemic pancreatitis.
Yadav D, Pitchumoni CS
J Clin Gastroenterol 2003 Jan;36(1):54-62. doi: 10.1097/00004836-200301000-00016. PMID: 12488710
Apolipoprotein E and complement C3 polymorphism and their role in the response to gemfibrozil and low fat low cholesterol therapy.
Nemeth A, Szakmary K, Kramer J, Dinya E, Pados G, Fust G, Huettinger M
Eur J Clin Chem Clin Biochem 1995 Nov;33(11):799-804. doi: 10.1515/cclm.1995.33.11.799. PMID: 8620056
Hyperlipidaemia, alcohol abuse and acute pancreatitis.
Dickson AP, O'Neill J, Imrie CW
Br J Surg 1984 Sep;71(9):685-8. doi: 10.1002/bjs.1800710913. PMID: 6206908

Clinical prediction guides

Dysbetalipoproteinaemia: a mixed hyperlipidaemia of remnant lipoproteins due to mutations in apolipoprotein E.
Marais AD, Solomon GA, Blom DJ
Crit Rev Clin Lab Sci 2014 Feb;51(1):46-62. Epub 2014 Jan 9 doi: 10.3109/10408363.2013.870526. PMID: 24405372
Genetic bases of hypertriglyceridemic phenotypes.
Johansen CT, Hegele RA
Curr Opin Lipidol 2011 Aug;22(4):247-53. doi: 10.1097/MOL.0b013e3283471972. PMID: 21519249
Apolipoprotein E and complement C3 polymorphism and their role in the response to gemfibrozil and low fat low cholesterol therapy.
Nemeth A, Szakmary K, Kramer J, Dinya E, Pados G, Fust G, Huettinger M
Eur J Clin Chem Clin Biochem 1995 Nov;33(11):799-804. doi: 10.1515/cclm.1995.33.11.799. PMID: 8620056
The low density lipoprotein receptor.
Schneider WJ
Biochim Biophys Acta 1989 May 9;988(2):303-17. doi: 10.1016/0304-4157(89)90023-3. PMID: 2655710
The effects of carbohydrate, fat and total energy adjustment of Fredrickson's type IIb hyperlipoproteinaemia.
Watermeyer GS, Manning E
S Afr Med J 1977 Jan 15;51(3):71-3. PMID: 189446

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...