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Adenofibroma

MedGen UID:
1325
•Concept ID:
C0001422
•
Neoplastic Process
Synonym: Adenofibromas
SNOMED CT: Benign adenofibroma (1157241000)
 
Monarch Initiative: MONDO:0006071

Definition

A benign neoplasm characterized by the presence of connective tissue stroma and epithelial structures. It occurs in the ovary, fallopian tube, uterine corpus, and cervix. Cases of adenofibroma of the ovary with low grade malignant potential have also been reported. [from MONDO]

Professional guidelines

PubMed

Mammotome biopsy under ultrasound control in the diagnostics and treatment of nodular breast lesions - own experience.
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Clear cell carcinoma of the ovary: is there a role of histology-specific treatment?
Takano M, Tsuda H, Sugiyama T
J Exp Clin Cancer Res 2012 Jun 1;31(1):53. doi: 10.1186/1756-9966-31-53. PMID: 22655678Free PMC Article
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Recent clinical studies

Etiology

Intrahepatic cholangiocarcinoma: typical features, uncommon variants, and controversial related entities.
Zen Y
Hum Pathol 2023 Feb;132:197-207. Epub 2022 Jun 11 doi: 10.1016/j.humpath.2022.06.001. PMID: 35697170
Clear cell carcinoma of the ovary: is there a role of histology-specific treatment?
Takano M, Tsuda H, Sugiyama T
J Exp Clin Cancer Res 2012 Jun 1;31(1):53. doi: 10.1186/1756-9966-31-53. PMID: 22655678Free PMC Article
Fibroadenoma.
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Wang DY, Fentiman IS
Breast Cancer Res Treat 1985;6(1):5-36. doi: 10.1007/BF01806008. PMID: 3902125

Diagnosis

Intrahepatic cholangiocarcinoma: typical features, uncommon variants, and controversial related entities.
Zen Y
Hum Pathol 2023 Feb;132:197-207. Epub 2022 Jun 11 doi: 10.1016/j.humpath.2022.06.001. PMID: 35697170
My approach to the interpretation of endometrial biopsies and curettings.
McCluggage WG
J Clin Pathol 2006 Aug;59(8):801-12. doi: 10.1136/jcp.2005.029702. PMID: 16873562Free PMC Article
Fibroadenoma.
Dent DM, Cant PJ
World J Surg 1989 Nov-Dec;13(6):706-10. doi: 10.1007/BF01658418. PMID: 2696223
Tumorigenic aspects.
Kirk ME
Int J Gynaecol Obstet 1978-1979;16(6):473-8. doi: 10.1002/j.1879-3479.1979.tb00952.x. PMID: 39811
Developments in mammography.
Wolfe JN
Am J Obstet Gynecol 1976 Feb 1;124(3):312-23. doi: 10.1016/0002-9378(76)90164-2. PMID: 174430

Therapy

Clear cell carcinoma of the ovary: is there a role of histology-specific treatment?
Takano M, Tsuda H, Sugiyama T
J Exp Clin Cancer Res 2012 Jun 1;31(1):53. doi: 10.1186/1756-9966-31-53. PMID: 22655678Free PMC Article
Breast lumps.
Townsend CM Jr
Clin Symp 1980;32(2):1-32. PMID: 7018816
Tumorigenic aspects.
Kirk ME
Int J Gynaecol Obstet 1978-1979;16(6):473-8. doi: 10.1002/j.1879-3479.1979.tb00952.x. PMID: 39811
Breast adenomas.
Hertel BF, Zaloudek C, Kempson RL
Cancer 1976 Jun;37(6):2891-905. doi: 10.1002/1097-0142(197606)37:6<2891::aid-cncr2820370647>3.0.co;2-p. PMID: 949710
Melphalan, medphalan & merphalan.
IARC Monogr Eval Carcinog Risk Chem Man 1975;9:167-80. PMID: 791831

Prognosis

Endometrioid adenofibroma of ovary: A case report and review of literature.
Tong HC, Li YC, Li LY, Xu HT, Ma S, Zhang WL, Wildes T, Yang LH, Wang E
Medicine (Baltimore) 2023 Feb 22;102(8):e32965. doi: 10.1097/MD.0000000000032965. PMID: 36827035
Mucinous Neoplasms of the Ovary: Radiologic-Pathologic Correlation.
Marko J, Marko KI, Pachigolla SL, Crothers BA, Mattu R, Wolfman DJ
Radiographics 2019 Jul-Aug;39(4):982-997. doi: 10.1148/rg.2019180221. PMID: 31283462Free PMC Article
Pathology of Endometrioid and Clear Cell Carcinoma of the Ovary.
Fadare O, Parkash V
Surg Pathol Clin 2019 Jun;12(2):529-564. doi: 10.1016/j.path.2019.01.009. PMID: 31097114
Synchronous Pulmonary Adenofibroma and Solitary Fibrous Tumor: Case Report and Review of the Literature.
Olson NJ, Czum JM, de Abreu FB, Linos K, Black CC
Int J Surg Pathol 2019 May;27(3):322-327. Epub 2018 Oct 26 doi: 10.1177/1066896918807302. PMID: 30360665
Clear cell carcinoma of the ovary: is there a role of histology-specific treatment?
Takano M, Tsuda H, Sugiyama T
J Exp Clin Cancer Res 2012 Jun 1;31(1):53. doi: 10.1186/1756-9966-31-53. PMID: 22655678Free PMC Article

Clinical prediction guides

Intrahepatic cholangiocarcinoma: typical features, uncommon variants, and controversial related entities.
Zen Y
Hum Pathol 2023 Feb;132:197-207. Epub 2022 Jun 11 doi: 10.1016/j.humpath.2022.06.001. PMID: 35697170
Robotic enucleation of a biliary adenofibroma.
Blears E, Uemura T, Bunker M
BMJ Case Rep 2021 Aug 10;14(8) doi: 10.1136/bcr-2021-242737. PMID: 34376413Free PMC Article
Advances in salivary gland pathology.
Cheuk W, Chan JK
Histopathology 2007 Jul;51(1):1-20. Epub 2007 May 31 doi: 10.1111/j.1365-2559.2007.02719.x. PMID: 17539914
Uterine adenomyoma: a clinicopathologic review of 26 cases and a review of the literature.
Tahlan A, Nanda A, Mohan H
Int J Gynecol Pathol 2006 Oct;25(4):361-5. doi: 10.1097/01.pgp.0000209570.08716.b3. PMID: 16990713
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Delahunt B, Velickovic M, Grebe SK
Expert Rev Anticancer Ther 2001 Dec;1(4):576-84. doi: 10.1586/14737140.1.4.576. PMID: 12113090

Recent systematic reviews

Imaging features of biliary adenofibroma of the liver with malignant transformation: a case report with literature review.
Hu W, Zhao Y, Liu Y, Hua Z, Liu A
BMC Med Imaging 2022 Mar 17;22(1):47. doi: 10.1186/s12880-022-00775-9. PMID: 35296268Free PMC Article

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