U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Unicystic Ameloblastoma

MedGen UID:
105344
•Concept ID:
C0457521
•
Neoplastic Process
Synonyms: Ameloblastoma, Unicystic Type; Cystogenic Ameloblastoma; Unicystic ameloblastoma
SNOMED CT: Unicystic ameloblastoma (278385006)

Definition

An ameloblastoma that presents as a unilocular cyst. It usually arises from the mandible. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnicystic Ameloblastoma

Professional guidelines

PubMed

Cystic Lesions of the Jaws: The Top 10 Differential Diagnoses to Ponder.
McLean AC, Vargas PA
Head Neck Pathol 2023 Mar;17(1):85-98. Epub 2023 Mar 16 doi: 10.1007/s12105-023-01525-1. PMID: 36928736Free PMC Article
Radical vs conservative treatment of intraosseous ameloblastoma: Systematic review and meta-analysis.
Hendra FN, Natsir Kalla DS, Van Cann EM, de Vet HCW, Helder MN, Forouzanfar T
Oral Dis 2019 Oct;25(7):1683-1696. Epub 2019 Jan 1 doi: 10.1111/odi.13014. PMID: 30548549
Unicystic ameloblastoma in children: systematic review of clinicopathological features and treatment outcomes.
Seintou A, Martinelli-Kläy CP, Lombardi T
Int J Oral Maxillofac Surg 2014 Apr;43(4):405-12. Epub 2014 Feb 3 doi: 10.1016/j.ijom.2014.01.003. PMID: 24503101

Recent clinical studies

Etiology

Recurrent tumors of ameloblastoma: Clinicopathologic features and diagnostic outcome.
Nwoga MC
Niger J Clin Pract 2022 Oct;25(10):1771-1777. doi: 10.4103/njcp.njcp_82_22. PMID: 36308255
Unicystic ameloblastoma: analysis of surgical management and recurrence risk factors.
Titinchi F, Brennan PA
Br J Oral Maxillofac Surg 2022 Apr;60(3):337-342. Epub 2021 Aug 8 doi: 10.1016/j.bjoms.2021.07.022. PMID: 34996630
Radical vs conservative treatment of intraosseous ameloblastoma: Systematic review and meta-analysis.
Hendra FN, Natsir Kalla DS, Van Cann EM, de Vet HCW, Helder MN, Forouzanfar T
Oral Dis 2019 Oct;25(7):1683-1696. Epub 2019 Jan 1 doi: 10.1111/odi.13014. PMID: 30548549
The occurrence and pattern of ameloblastoma in children and adolescents: an Indian institutional study of 41 years and review of the literature.
Bansal S, Desai RS, Shirsat P, Prasad P, Karjodkar F, Andrade N
Int J Oral Maxillofac Surg 2015 Jun;44(6):725-31. Epub 2015 Feb 2 doi: 10.1016/j.ijom.2015.01.002. PMID: 25655766
Ameloblastoma in children.
Ord RA, Blanchaert RH Jr, Nikitakis NG, Sauk JJ
J Oral Maxillofac Surg 2002 Jul;60(7):762-70; discussion, 770-1. doi: 10.1053/joms.2002.33242. PMID: 12089689

Diagnosis

Pediatric Odontogenic Tumors.
Liu Y, Smith MH, Patel PB, Bilodeau EA
Pediatr Dev Pathol 2023 Nov-Dec;26(6):583-595. Epub 2023 Nov 30 doi: 10.1177/10935266231200115. PMID: 38032744
Cystic Lesions of the Jaws: The Top 10 Differential Diagnoses to Ponder.
McLean AC, Vargas PA
Head Neck Pathol 2023 Mar;17(1):85-98. Epub 2023 Mar 16 doi: 10.1007/s12105-023-01525-1. PMID: 36928736Free PMC Article
Unicystic ameloblastoma: analysis of surgical management and recurrence risk factors.
Titinchi F, Brennan PA
Br J Oral Maxillofac Surg 2022 Apr;60(3):337-342. Epub 2021 Aug 8 doi: 10.1016/j.bjoms.2021.07.022. PMID: 34996630
Ameloblastoma in children.
Ord RA, Blanchaert RH Jr, Nikitakis NG, Sauk JJ
J Oral Maxillofac Surg 2002 Jul;60(7):762-70; discussion, 770-1. doi: 10.1053/joms.2002.33242. PMID: 12089689
Unicystic ameloblastoma.
Marks R, Block M, Sanusi ID, Lowe B, Gross BD
Int J Oral Surg 1983 Jun;12(3):186-9. doi: 10.1016/s0300-9785(83)80065-9. PMID: 6411640

Therapy

Expression of nucleostemin in odontogenic cysts and tumors.
Andisheh-Tadbir A, Ranjbar MA, Shiri AA, Mardani M
Exp Mol Pathol 2020 Apr;113:104376. Epub 2020 Jan 9 doi: 10.1016/j.yexmp.2020.104376. PMID: 31926976
Expression of TP53 and IL-1α in unicystic ameloblastoma predicts the efficacy of marsupialization treatment.
Zhang X, Liu L, Yang X, Wang L, Zhang C, Hu Y
Medicine (Baltimore) 2018 Feb;97(6):e9795. doi: 10.1097/MD.0000000000009795. PMID: 29419674Free PMC Article
Recurrence rates of intraosseous ameloblastomas of the jaws: a systematic review of conservative versus aggressive treatment approaches and meta-analysis of non-randomized studies.
Antonoglou GN, Sándor GK
J Craniomaxillofac Surg 2015 Jan;43(1):149-57. Epub 2014 Oct 31 doi: 10.1016/j.jcms.2014.10.027. PMID: 25465490
Is there a role for enucleation in the management of ameloblastoma?
Pogrel MA, Montes DM
Int J Oral Maxillofac Surg 2009 Aug;38(8):807-12. Epub 2009 Mar 17 doi: 10.1016/j.ijom.2009.02.018. PMID: 19297131
Recurrence related to treatment modalities of unicystic ameloblastoma: a systematic review.
Lau SL, Samman N
Int J Oral Maxillofac Surg 2006 Aug;35(8):681-90. Epub 2006 Jun 16 doi: 10.1016/j.ijom.2006.02.016. PMID: 16782308

Prognosis

The Mutational Profile of Unicystic Ameloblastoma.
Heikinheimo K, Huhtala JM, Thiel A, Kurppa KJ, Heikinheimo H, Kovac M, Kragelund C, Warfvinge G, Dawson H, Elenius K, Ristimäki A, Baumhoer D, Morgan PR
J Dent Res 2019 Jan;98(1):54-60. Epub 2018 Sep 14 doi: 10.1177/0022034518798810. PMID: 30216733
Comparative Study of the Minichromosome Maintenance Proteins Complex (MCM 4/5/6) in Ameloblastoma and Unicystic Ameloblastoma.
Apellániz D, Pereira-Prado V, Sicco E, Vigil-Bastitta G, González-González R, Mosqueda-Taylor A, Molina-Frechero N, Hernandez M, Sánchez-Romero C, Bologna-Molina R
Int J Surg Pathol 2018 Dec;26(8):714-720. Epub 2018 May 30 doi: 10.1177/1066896918778341. PMID: 29845895
Expression of TP53 and IL-1α in unicystic ameloblastoma predicts the efficacy of marsupialization treatment.
Zhang X, Liu L, Yang X, Wang L, Zhang C, Hu Y
Medicine (Baltimore) 2018 Feb;97(6):e9795. doi: 10.1097/MD.0000000000009795. PMID: 29419674Free PMC Article
Premolar Cystic Ameloblastoma in a Child.
Pathak S, Sonalika WG, Hs V, Tegginammani AS
J Coll Physicians Surg Pak 2017 Jan;27(1):47-48. PMID: 28292369
Ameloblastoma in children.
Ord RA, Blanchaert RH Jr, Nikitakis NG, Sauk JJ
J Oral Maxillofac Surg 2002 Jul;60(7):762-70; discussion, 770-1. doi: 10.1053/joms.2002.33242. PMID: 12089689

Clinical prediction guides

Differential expression of PEA3 in odontogenic cysts and tumors.
Tun KM, Kitkumthorn N, Bumalee D, Arayapisit T, Lapthanasupkul P
J Oral Pathol Med 2023 Sep;52(8):777-785. Epub 2023 Aug 7 doi: 10.1111/jop.13476. PMID: 37549030
A conservative approach for unicystic ameloblastoma: Retrospective clinic-pathologic analysis of 12 cases.
Leite-Lima F, Martins-Chaves RR, Fonseca FP, Brennan PA, de Castro WH, Gomez RS
J Oral Pathol Med 2023 Aug;52(7):654-659. Epub 2023 May 24 doi: 10.1111/jop.13453. PMID: 37224237
Recurrent tumours of ameloblastoma: Clinicopathologic features and diagnostic outcome.
Nwoga MC
Niger J Clin Pract 2022 Sep;25(9):1529-1534. doi: 10.4103/njcp.njcp_82_22. PMID: 36149215
Expression of TP53 and IL-1α in unicystic ameloblastoma predicts the efficacy of marsupialization treatment.
Zhang X, Liu L, Yang X, Wang L, Zhang C, Hu Y
Medicine (Baltimore) 2018 Feb;97(6):e9795. doi: 10.1097/MD.0000000000009795. PMID: 29419674Free PMC Article
CD10 and osteopontin expression in dentigerous cyst and ameloblastoma.
Masloub SM, Abdel-Azim AM, Elhamid ES
Diagn Pathol 2011 May 24;6:44. doi: 10.1186/1746-1596-6-44. PMID: 21609487Free PMC Article

Recent systematic reviews

A meta-analysis on the presentation of Unicystic Ameloblastoma in the jaws and the consequences for their treatment.
da Silva YS, Sohal KS, Stoelinga PJW, Grillo R
J Stomatol Oral Maxillofac Surg 2022 Oct;123(5):e433-e438. Epub 2022 Jan 10 doi: 10.1016/j.jormas.2022.01.004. PMID: 35017129
Radical vs conservative treatment of intraosseous ameloblastoma: Systematic review and meta-analysis.
Hendra FN, Natsir Kalla DS, Van Cann EM, de Vet HCW, Helder MN, Forouzanfar T
Oral Dis 2019 Oct;25(7):1683-1696. Epub 2019 Jan 1 doi: 10.1111/odi.13014. PMID: 30548549
Recurrence rates of intraosseous ameloblastomas of the jaws: a systematic review of conservative versus aggressive treatment approaches and meta-analysis of non-randomized studies.
Antonoglou GN, Sándor GK
J Craniomaxillofac Surg 2015 Jan;43(1):149-57. Epub 2014 Oct 31 doi: 10.1016/j.jcms.2014.10.027. PMID: 25465490
Unicystic ameloblastoma in children: systematic review of clinicopathological features and treatment outcomes.
Seintou A, Martinelli-Kläy CP, Lombardi T
Int J Oral Maxillofac Surg 2014 Apr;43(4):405-12. Epub 2014 Feb 3 doi: 10.1016/j.ijom.2014.01.003. PMID: 24503101
Recurrence related to treatment modalities of unicystic ameloblastoma: a systematic review.
Lau SL, Samman N
Int J Oral Maxillofac Surg 2006 Aug;35(8):681-90. Epub 2006 Jun 16 doi: 10.1016/j.ijom.2006.02.016. PMID: 16782308

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...