PubMed

Biological, clinical, and ethical advances of placebo effects.

Authors

Finniss DG, Kaptchuk TJ, Miller F, Benedetti F.

Journal

Lancet. 2010 Feb 20;375(9715):686-95. doi: 10.1016/S0140-6736(09)61706-2.

Affiliation

Comment in

Abstract

For many years, placebos have been defined by their inert content and their use as controls in clinical trials and treatments in clinical practice. Recent research shows that placebo effects are genuine psychobiological events attributable to the overall therapeutic context, and that these effects can be robust in both laboratory and clinical settings. There is also evidence that placebo effects can exist in clinical practice, even if no placebo is given. Further promotion and integration of laboratory and clinical research will allow advances in the ethical use of placebo mechanisms that are inherent in routine clinical care, and encourage the use of treatments that stimulate placebo effects.

Copyright 2010 Elsevier Ltd. All rights reserved.

PMID

20171404 [PubMed - indexed for MEDLINE]

PMCID

PMC2832199 Free Full Text
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