Homo sapiens complex locus SATB2, encoding SATB homeobox 2.
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SUMMARY back to top
RefSeq summary
[SATB2] This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq].

RefSeq annotates 3 representative transcripts (NM included in AceView variants .a, .b and .c), but Homo sapiens cDNA sequences in GenBank, dbEST, Trace and SRA, filtered against clone rearrangements, coaligned on the genome and clustered in a minimal non-redundant way by the manually supervised AceView program, support at least 8 spliced variants.

AceView synopsis, each blue text links to tables and details
Note that this locus is complex: it appears to produce several proteins with no sequence overlap.
Expression: According to AceView, this gene is well expressed, 1.3 times the average gene in this release. The sequence of this gene is defined by 160 GenBank accessions from 143 cDNA clones, some from brain (seen 45 times), whole brain (9), colon (8), hepatocellular carcinoma (7), hippocampus (6), liver (5), prostate tumor (5) and 28 other tissues. We annotate structural defects or features in 25 cDNA clones.
Alternative mRNA variants and regulation: The gene contains 18 distinct gt-ag introns. Transcription produces 10 different mRNAs, 8 alternatively spliced variants and 2 unspliced forms. There are 6 probable alternative promotors, 3 non overlapping alternative last exons and 2 validated alternative polyadenylation sites (see the diagram). The mRNAs appear to differ by truncation of the 5' end, truncation of the 3' end, presence or absence of 5 cassette exons, overlapping exons with different boundaries. 1180 bp of this gene are antisense to spliced gene FLJ32063, 213 to seydu, raising the possibility of regulated alternate expression.
2 variants were isolated in vivo, despite the fact that they are predicted targets of nonsense mediated mRNA decay (NMD).
Efficacy of translation may be reduced by the presence of a shorter translated product (uORF) initiating at an AUG upstream of the main open reading frame (in variant cAug10, dAug10).
Function: There are 8 articles specifically referring to this gene in PubMed. Functionally, the gene has been tested for association to diseases (OMIM: Cleft palate, isolated; Other sources: Abnormalities, Multiple; Cleft Palate; Cleft palate and mental retardation; Mental Retardation) and proposed to participate in processes (cartilage development, chromatin remodeling, embryonic pattern specification, embryonic skeletal system morphogenesis, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, neuron migration, osteoblast development, palate development, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent). Proteins are expected to have molecular functions (chromatin binding, protein binding, sequence-specific DNA binding, transcription factor activity) and to localize in various compartments (membrane, mitochondrion, histone deacetylase complex, nuclear matrix, nucleus, transcription factor complex). A putative protein interactor has been described (SKOR1ANDPIAS1).
Protein coding potential: 8 spliced mRNAs putatively encode good proteins, altogether 6 different isoforms (5 complete, 1 partial), some containing domains CUT domain, Homeobox domain [Pfam], some transmembrane domains, a coiled coil stretch [Psort2]. The remaining 2 mRNA variants (2 unspliced) appear not to encode good proteins. Finally proteins from this gene may be modulated by phosphorylation; sumoylation, as detailed at PhosphoSite.

Please quote: AceView: a comprehensive cDNA-supported gene and transcripts annotation, Genome Biology 2006, 7(Suppl 1):S12.
Map on chromosome 2, links to other databases and other names
Map: This gene SATB2 maps on chromosome 2, at 2q33 according to Entrez Gene. In AceView, it covers 202.04 kb, from 200335994 to 200133952 (NCBI 37, August 2010), on the reverse strand.
Links to: manual annotations from OMIM_119540, PhosphoSite, the SNP view, gene overviews from Entrez Gene 23314, GeneCards, expression data from ECgene, UniGene, molecular and other annotations from UCSC, or our GOLD analysis.
The previous AceView annotation is here.
Other names: The gene is also known as SATB2, FLJ21474, FLJ32076, KIAA1034, MGC119474 or MGC119477, LOC23314. It has been described as DNA-binding protein SATB2, OTTHUMP00000163655, OTTHUMP00000205774, OTTHUMP00000205775, OTTHUMP00000208037, OTTHUMP00000208038, SATB family member 2, special AT-rich sequence-binding protein 2.
Closest AceView homologs in other species ?
The closest mouse gene, according to BlastP, is the AceView gene 9130024F11RikandSatb2 (e=0.0).
The closest C.elegans genes, according to BlastP, are the AceView/WormGenes ceh-48 (e=0.001), ceh-38 (e=0.009), which may contain interesting functional annotation.
The closest A.thaliana gene, according to BlastP, is the AceView gene CYCB2\;3 (e=0.30), which may contain interesting functional annotation
RNA_seq discoveries back to top
Expression/conservation in primates tissues evaluated by cross-mapping to human. back to top
SATB2 Gene expression in 15 primates, 16 tissues, from the NHPRTR project in sFPKM BAB SkeletalMuscle WholeBlood CHP Kidney Liver Lung Spleen CMC CMM Cerebellum HUM Brain Colon Heart LymphNode Ovary Testis JMI BoneMarrow MLM OWL PTM RMC RMI Pituitary SQM Thymus MST SMY RTL 0.19 3.33 1.26 0.48 0.11 0.89 0.29 0.72 18.8 10.1 1.18 5.40 2.35 0.55 2.90 3.33 2.70 5.79 0.51 3.57 1.45 18.8 10.8 0.68 1.26 5.04 0.26 0.42 0.72 2.52 2.70 3.33 0.39 35.1 43.2 0.22 3.57 0.68 0.26 0.32 0.51 0.51 32.8 2.19 0.51 7.64 0.36 0.16 0.27 61.1 2.19 2.70 23.2 0.32 0.19 0.21 1.35 2.90 21.6 0.39 0.19 0.19 4.10 0.11 0.19 0.21 0.10 0.08 30.6 2.52 35.1 0.55 5.04 0.16 0.24 0.45 0.63 0.36 28.5 0.17 1.45 26.6 0.19 35.1 0.12 2.52 0.42 0.22 0.24 0.10 0.32 0.22 0.72 0.24 3.33 0.12 0.22 0.18 1.02 0.12 35.1 14.3 37.6 0.45 4.71 0.32 0.26 0.42 0.13 1.26 0.39 30.6 0.32 0.17 0.12 23.2 0.06 3.57 0.18 0.16 0.09 23.2 0.18 0.39 0.48 0.15 0.27 0.07 0.78 1.66 0.55 65.5 43.2 0.10 2.90 0.55 0.34 0.32 0.36 0.27 2.19 1.26 0.26 1.35 30.6 2.19 0.45 Expression quantiles None Weak 1 2 3 4 5 6 7 8 10 20 This gene All genes log2 distributions RNA-seq gene expression profile across 16 selected tissues from the Non-Human Primates Reference Transcriptome Resource (link to NHPRTR project).
- Primates: Apes (HUM: Human (Illumina BodyMap 2), CHP: Chimpanzee), Old World monkeys (PTM: Pig-Tailed Macaque, JMI Japanese Macaque, RMI Rhesus Macaque Indian, RMC Rhesus Macaque Chinese, CMM Cynomolgus Macaque Mauritian, CMC Cynomolgus Macaque Chinese, BAB Olive Baboon, SMY Sooty Mangabey); New World monkeys (MST common Marmoset, SQM Squirrel Monkey, OWL Owl Monkey); and Lemurs (MLM Mouse Lemur, RTL Ring-Tailed Lemur).
- The level for significantly expressed genes is color coded in 8 equal sized bins (light to dark green). Light gray is for weak not-accurately measured expression (2 to 8 reads above intergenic background); dark gray for no expression or no sequence conservation (0 read in gene). The plot to the right shows the distribution of measured expression values in all tissues for all genes (blue) and for this gene (green), in Magic index = log2(1000 sFPKM).
You may also examine the strand-specific genome coverage plots on the experimental AceView/Magic hub at UCSC, by tissue or by species. Tracks may be slow to load; please reload if some tracks come up yellow-greenish, and thanks to UCSC for the great work!.
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          Complete gene on genome diagram: back to top
Please choose between the zoomable GIF version., and the HTML5/SVG version.
This diagram shows in true scale the gene on the genome, the mRNAs and the cDNA clones.
Compact gene diagram back to top
Gene SATB2 5' 3' encoded on minus strand of chromosome 2 from 200,335,994 to 200,133,952 77 411 3086 4228 4528 5425 4320 6112 8481 7483 7577 a [NM] 3645 3086 4228 4528 5425 4320 6112 8481 7483 7577 b [NM] 77 411 3086 4228 4528 5425 4320 6112 8481 7483 7577 c [NM] 6 411 3086 29 6112 8481 7483 7577 d 1 4528 5425 4320 e 3645 3086 59 43 f j-u 411 3086 4228 h 4320 g i-u 5kb 0 273 bp exon 4303 bp [gt-ag] intron 2 GenBank accessions 75 RNA-seq supporting reads 74 Brain 1 Other (also 311 Primates bodymap) 81 bp exon 4355 bp [gt-ag] intron 12 GenBank accessions 399 RNA-seq supporting reads 12 UHR pooled cells 380 Brain 7 Neuroblastoma (also 835 Primates bodymap) 228 bp exon 228 bp exon 22354 bp [gt-ag] intron 25 GenBank accessions 3061 RNA-seq supporting reads 972 UHR pooled cells 1428 Brain 18 Blood 619 Neuroblastoma 24 Other (also 1088 Primates bodymap) 177 bp exon 51517 bp [gt-ag] intron 15 GenBank accessions 4213 RNA-seq supporting reads 1204 UHR pooled cells 2274 Brain 39 Blood 647 Neuroblastoma 49 Other (also 4046 Primates bodymap) 127 bp exon 1206 bp [gt-ag] intron 15 GenBank accessions 4513 RNA-seq supporting reads 1354 UHR pooled cells 2295 Brain 58 Blood 740 Neuroblastoma 66 Other (also 4209 Primates bodymap) 124 bp exon 11656 bp [gt-ag] intron 18 GenBank accessions 5407 RNA-seq supporting reads 1527 UHR pooled cells 2868 Brain 66 Blood 868 Neuroblastoma 78 Other (also 6017 Primates bodymap) 103 bp exon 19431 bp [gt-ag] intron 23 GenBank accessions 4297 RNA-seq supporting reads 1286 UHR pooled cells 2204 Brain 56 Blood 687 Neuroblastoma 64 Other (also 2797 Primates bodymap) 473 bp exon 19790 bp [gt-ag] intron 25 GenBank accessions 6087 RNA-seq supporting reads 1773 UHR pooled cells 3232 Brain 32 Blood 999 Neuroblastoma 51 Other (also 1506 Primates bodymap) 213 bp exon 4739 bp [gt-ag] intron 20 GenBank accessions 8461 RNA-seq supporting reads 2432 UHR pooled cells 4622 Brain 44 Blood 1301 Neuroblastoma 62 Other (also 2925 Primates bodymap) 156 bp exon 14845 bp [gt-ag] intron 22 GenBank accessions 7461 RNA-seq supporting reads 2131 UHR pooled cells 4106 Brain 16 Blood 1160 Neuroblastoma 48 Other (also 1890 Primates bodymap) 198 bp exon 36087 bp [gt-ag] intron 17 GenBank accessions 7560 RNA-seq supporting reads 2239 UHR pooled cells 4123 Brain 30 Blood 1132 Neuroblastoma 36 Other (also 1097 Primates bodymap) 3173 bp exon 2 accessions, NM_001172517.1 some from brain (seen once) Validated 3' end, 1 accession 3173 bp exon 758 bp exon 1242 bp [gt-ag] intron 12 GenBank accessions 3633 RNA-seq supporting reads 1298 UHR pooled cells 1701 Brain 28 Blood 588 Neuroblastoma 18 Other (also 896 Primates bodymap) 228 bp exon 228 bp exon 22354 bp [gt-ag] intron 25 GenBank accessions 3061 RNA-seq supporting reads 972 UHR pooled cells 1428 Brain 18 Blood 619 Neuroblastoma 24 Other (also 1088 Primates bodymap) 177 bp exon 51517 bp [gt-ag] intron 15 GenBank accessions 4213 RNA-seq supporting reads 1204 UHR pooled cells 2274 Brain 39 Blood 647 Neuroblastoma 49 Other (also 4046 Primates bodymap) 127 bp exon 1206 bp [gt-ag] intron 15 GenBank accessions 4513 RNA-seq supporting reads 1354 UHR pooled cells 2295 Brain 58 Blood 740 Neuroblastoma 66 Other (also 4209 Primates bodymap) 124 bp exon 11656 bp [gt-ag] intron 18 GenBank accessions 5407 RNA-seq supporting reads 1527 UHR pooled cells 2868 Brain 66 Blood 868 Neuroblastoma 78 Other (also 6017 Primates bodymap) 103 bp exon 19431 bp [gt-ag] intron 23 GenBank accessions 4297 RNA-seq supporting reads 1286 UHR pooled cells 2204 Brain 56 Blood 687 Neuroblastoma 64 Other (also 2797 Primates bodymap) 473 bp exon 19790 bp [gt-ag] intron 25 GenBank accessions 6087 RNA-seq supporting reads 1773 UHR pooled cells 3232 Brain 32 Blood 999 Neuroblastoma 51 Other (also 1506 Primates bodymap) 213 bp exon 4739 bp [gt-ag] intron 20 GenBank accessions 8461 RNA-seq supporting reads 2432 UHR pooled cells 4622 Brain 44 Blood 1301 Neuroblastoma 62 Other (also 2925 Primates bodymap) 156 bp exon 14845 bp [gt-ag] intron 22 GenBank accessions 7461 RNA-seq supporting reads 2131 UHR pooled cells 4106 Brain 16 Blood 1160 Neuroblastoma 48 Other (also 1890 Primates bodymap) 198 bp exon 36087 bp [gt-ag] intron 17 GenBank accessions 7560 RNA-seq supporting reads 2239 UHR pooled cells 4123 Brain 30 Blood 1132 Neuroblastoma 36 Other (also 1097 Primates bodymap) 3173 bp exon 14 accessions, NM_001172509.1 some from brain (seen 10 times) embryonic stem cells embryoid bodiesderived from H1 H7 and H9 cells (once) fetal brain (once) capped 5' end, 9 accessions 3173 bp exon 258 bp exon 258 bp exon 477 bp uORF 10481 bp [gt-ag] intron 3 GenBank accessions 74 RNA-seq supporting reads 74 Brain (also 18 Primates bodymap) 81 bp exon 477 bp uORF 4355 bp [gt-ag] intron 12 GenBank accessions 399 RNA-seq supporting reads 12 UHR pooled cells 380 Brain 7 Neuroblastoma (also 835 Primates bodymap) 228 bp exon 477 bp uORF 228 bp exon 22354 bp [gt-ag] intron 25 GenBank accessions 3061 RNA-seq supporting reads 972 UHR pooled cells 1428 Brain 18 Blood 619 Neuroblastoma 24 Other (also 1088 Primates bodymap) 477 bp uORF 177 bp exon 177 bp exon 51517 bp [gt-ag] intron 15 GenBank accessions 4213 RNA-seq supporting reads 1204 UHR pooled cells 2274 Brain 39 Blood 647 Neuroblastoma 49 Other (also 4046 Primates bodymap) 127 bp exon 127 bp exon 1206 bp [gt-ag] intron 15 GenBank accessions 4513 RNA-seq supporting reads 1354 UHR pooled cells 2295 Brain 58 Blood 740 Neuroblastoma 66 Other (also 4209 Primates bodymap) 124 bp exon 124 bp exon 11656 bp [gt-ag] intron 18 GenBank accessions 5407 RNA-seq supporting reads 1527 UHR pooled cells 2868 Brain 66 Blood 868 Neuroblastoma 78 Other (also 6017 Primates bodymap) 103 bp exon 103 bp exon 19431 bp [gt-ag] intron 23 GenBank accessions 4297 RNA-seq supporting reads 1286 UHR pooled cells 2204 Brain 56 Blood 687 Neuroblastoma 64 Other (also 2797 Primates bodymap) 473 bp exon 473 bp exon 19790 bp [gt-ag] intron 25 GenBank accessions 6087 RNA-seq supporting reads 1773 UHR pooled cells 3232 Brain 32 Blood 999 Neuroblastoma 51 Other (also 1506 Primates bodymap) 213 bp exon 213 bp exon 4739 bp [gt-ag] intron 20 GenBank accessions 8461 RNA-seq supporting reads 2432 UHR pooled cells 4622 Brain 44 Blood 1301 Neuroblastoma 62 Other (also 2925 Primates bodymap) 156 bp exon 156 bp exon 14845 bp [gt-ag] intron 22 GenBank accessions 7461 RNA-seq supporting reads 2131 UHR pooled cells 4106 Brain 16 Blood 1160 Neuroblastoma 48 Other (also 1890 Primates bodymap) 198 bp exon 198 bp exon 36087 bp [gt-ag] intron 17 GenBank accessions 7560 RNA-seq supporting reads 2239 UHR pooled cells 4123 Brain 30 Blood 1132 Neuroblastoma 36 Other (also 1097 Primates bodymap) 3444 bp exon 3444 bp exon 98 accessions, NM_015265.3 some from brain (seen 25 times) whole brain (8), hippocampus (6) hepatocellular carcinoma (5) prostate tumor (5) capped 5' end, 15 accessions 3444 bp exon 247 bp exon 247 bp exon 30 bp uORF 247 bp exon 4388 bp [gt-ag] intron 1 GenBank accession 5 RNA-seq supporting reads 5 Brain (also 4 Primates bodymap) 81 bp exon 81 bp exon 4355 bp [gt-ag] intron 12 GenBank accessions 399 RNA-seq supporting reads 12 UHR pooled cells 380 Brain 7 Neuroblastoma (also 835 Primates bodymap) 228 bp exon 228 bp exon 228 bp exon 22354 bp [gt-ag] intron 25 GenBank accessions 3061 RNA-seq supporting reads 972 UHR pooled cells 1428 Brain 18 Blood 619 Neuroblastoma 24 Other (also 1088 Primates bodymap) 177 bp exon 177 bp exon 84164 bp [gt-ag] intron 1 GenBank accession 28 RNA-seq supporting reads 4 UHR pooled cells 23 Brain 1 Neuroblastoma (also 12 Primates bodymap) 473 bp exon 473 bp exon 19790 bp [gt-ag] intron 25 GenBank accessions 6087 RNA-seq supporting reads 1773 UHR pooled cells 3232 Brain 32 Blood 999 Neuroblastoma 51 Other (also 1506 Primates bodymap) 213 bp exon 213 bp exon 4739 bp [gt-ag] intron 20 GenBank accessions 8461 RNA-seq supporting reads 2432 UHR pooled cells 4622 Brain 44 Blood 1301 Neuroblastoma 62 Other (also 2925 Primates bodymap) 156 bp exon 156 bp exon 14845 bp [gt-ag] intron 22 GenBank accessions 7461 RNA-seq supporting reads 2131 UHR pooled cells 4106 Brain 16 Blood 1160 Neuroblastoma 48 Other (also 1890 Primates bodymap) 198 bp exon 198 bp exon 36087 bp [gt-ag] intron 17 GenBank accessions 7560 RNA-seq supporting reads 2239 UHR pooled cells 4123 Brain 30 Blood 1132 Neuroblastoma 36 Other (also 1097 Primates bodymap) 698 bp exon 698 bp exon 2 accessions, some from brain (seen once) capped 5' end, 1 accession 698 bp exon 229 bp exon 229 bp exon 41865 bp [gt-ag] intron 1 GenBank accession 127 bp exon 1206 bp [gt-ag] intron 15 GenBank accessions 4513 RNA-seq supporting reads 1354 UHR pooled cells 2295 Brain 58 Blood 740 Neuroblastoma 66 Other (also 4209 Primates bodymap) 124 bp exon 11656 bp [gt-ag] intron 18 GenBank accessions 5407 RNA-seq supporting reads 1527 UHR pooled cells 2868 Brain 66 Blood 868 Neuroblastoma 78 Other (also 6017 Primates bodymap) 103 bp exon 19431 bp [gt-ag] intron 23 GenBank accessions 4297 RNA-seq supporting reads 1286 UHR pooled cells 2204 Brain 56 Blood 687 Neuroblastoma 64 Other (also 2797 Primates bodymap) 2291 bp exon 5 accessions, some from brain (seen once) colon (once), denis drash (once) eye (once), head neck (once) capped 5' end, 1 accession 2291 bp exon 272 bp exon 272 bp exon 1242 bp [gt-ag] intron 12 GenBank accessions 3633 RNA-seq supporting reads 1298 UHR pooled cells 1701 Brain 28 Blood 588 Neuroblastoma 18 Other (also 896 Primates bodymap) 228 bp exon 22354 bp [gt-ag] intron 25 GenBank accessions 3061 RNA-seq supporting reads 972 UHR pooled cells 1428 Brain 18 Blood 619 Neuroblastoma 24 Other (also 1088 Primates bodymap) 177 bp exon 177 bp exon 35497 bp [gt-ag] intron 1 GenBank accession 58 RNA-seq supporting reads 18 UHR pooled cells 20 Brain 1 Blood 17 Neuroblastoma 2 Other 311 bp exon 523 bp [gt-ag] intron 1 GenBank accession 42 RNA-seq supporting reads 28 UHR pooled cells 5 Brain 2 Blood 7 Neuroblastoma 2 accessions, some from brain (seen once) Validated 3' end, 1 accession 1175 bp exon 604 bp exon 604 bp exon 2 accessions 604 bp exon 103 bp exon 103 bp exon 4355 bp [gt-ag] intron 12 GenBank accessions 399 RNA-seq supporting reads 12 UHR pooled cells 380 Brain 7 Neuroblastoma (also 835 Primates bodymap) 228 bp exon 22354 bp [gt-ag] intron 25 GenBank accessions 3061 RNA-seq supporting reads 972 UHR pooled cells 1428 Brain 18 Blood 619 Neuroblastoma 24 Other (also 1088 Primates bodymap) 177 bp exon 177 bp exon 51517 bp [gt-ag] intron 15 GenBank accessions 4213 RNA-seq supporting reads 1204 UHR pooled cells 2274 Brain 39 Blood 647 Neuroblastoma 49 Other (also 4046 Primates bodymap) 2 accessions, some from brain (seen 2 times) capped 5' end, 2 accessions 120 bp exon 339 bp exon 339 bp exon 27 bp uORF 339 bp exon 339 bp exon 19431 bp [gt-ag] intron 23 GenBank accessions 4297 RNA-seq supporting reads 1286 UHR pooled cells 2204 Brain 56 Blood 687 Neuroblastoma 64 Other (also 2797 Primates bodymap) 303 bp exon 303 bp exon 4 accessions, some from colon (seen 4 times) 303 bp exon 629 bp exon 629 bp exon 3 accessions, some from brain (seen 2 times) 629 bp exon Alternative mRNAs are shown aligned from 5' to 3' on a virtual genome where introns have been shrunk to a minimal length. Exon size is proportional to length, intron height reflects the number of cDNAs supporting each intron, the small numbers show the support of the introns in deep sequencing (with details in mouse-over) . Introns of the same color are identical, of different colors are different. 'Good proteins' are pink, partial or not-good proteins are yellow, uORFs are green. 5' cap or3' poly A flags show completeness of the transcript.
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Sequences: click on the numbers to get the DNA back to top
mRNA variant mRNA matching the genome Best predicted protein 5' UTR 3' UTR uORF Upstream sequence Transcription
unit
pre-mRNA		 Downstream sequence
aAug10 5326 bp 733 aa 413 bp 2711 bp 2kb possibly including promoter 195609 bp 1kb
bAug10 5730 bp 733 aa 817 bp 2711 bp 2kb including Promoter 188597 bp 1kb
cAug10 5582 bp 733 aa 398 bp 2982 bp 474 bp 2kb including Promoter 202043 bp 1kb
dAug10 2471 bp 615 aa 387 bp 236 bp 27 bp 2kb including Promoter 193193 bp 1kb
eAug10 2874 bp 320 aa 213 bp 1698 bp 2kb including Promoter 77032 bp 1kb
fAug10 2163 bp 141 aa 126 bp 1611 bp 2kb possibly including promoter 61779 bp 1kb
gAug10 642 bp 134 aa 239 bp 24 bp 2kb possibly including promoter 20073 bp 1kb
hAug10 628 bp 104 aa 68 bp 245 bp 2kb including Promoter 78854 bp 1kb
iAug10-unspliced 629 bp 42 aa 297 bp 203 bp 2kb 629 bp 1kb
jAug10-unspliced 604 bp 40 aa 423 bp 58 bp 2kb 604 bp 1kb

Gene neighbors and Navigator on chromosome 2q33 back to top
C R FLJ32063 R G R D C I R P SATB2 G C R 100kb 0 larswaby, 2 accessions seydu, 3 accessions, 2 variants FLJ32063, 98 accessions 5 variants LOC729399, 7 accessions 3 variants fogeybo, 1 accession kloygabu, 2 accessions lyswaby, 1 accession cheymybo, 1 accession plogabu, 1 accession plargabu, 1 accession pleegabu, 1 accession plergabu, 1 accession plorgabu, 1 accession ploygabu, 1 accession skagabu, 1 accession stykly, 9 accessions skygabu, 4 accessions skugabu, 1 accession fergeybo, 2 accessions skergabu, 2 accessions shermybo, 1 accession skorgabu, 1 accession slagabu, 1 accession slargabu, 1 accession slawgabu, 3 accessions ranamo, 2 accessions, 2 variants sleygabu, 1 accession sahuyo, 1 accession sloygabu, 1 accession gogeybo, 7 accessions gargeybo, 1 accession narswaby, 2 accessions nawswaby, 3 accessions blumybo, 1 accession smugabu, 1 accession geegeybo, 1 accession noyswaby, 1 accession gergeybo, 2 accessions flormybo, 1 accession snagabu, 2 accessions chermybo, 1 accession kehomo, 2 accessions, 2 variants plagabu, 1 accession plygabu, 2 accessions plugabu, 1 accession lerswaby, 1 accession kohomo, 1 accession nyveybo, 1 accession pleygabu, 1 accession feygeybo, 2 accessions skargabu, 1 accession jawlu, 1 accession foygeybo, 1 accession skawgabu, 1 accession skeegabu, 1 accession skeygabu, 1 accession wanamo, 1 accession skoygabu, 1 accession gageybo, 1 accession slygabu, 1 accession slugabu, 1 accession stokly, 2 accessions sheymybo, 1 accession slogabu, 1 accession blymybo, 1 accession sleegabu, 1 accession slergabu, 1 accession moswaby, 1 accession rinamo, 1 accession jeelu, 1 accession runamo, 2 accessions, 2 variants gugeybo, 6 accessions gawgeybo, 1 accession sihuyo, 1 accession seystuby, 1 accession slanoybo, 1 accession smygabu, 1 accession neeswaby, 1 accession geekerbo, 1 accession smogabu, 2 accessions neyswaby, 1 accession flymybo, 1 accession smargabu, 1 accession slunoybo, 4 accessions fleemybo, 1 accession smawgabu, 1 accession fleymybo, 1 accession smeegabu, 6 accessions smergabu, 1 accession smeygabu, 2 accessions nuveybo, 11 accessions jorlu, 5 accessions floymybo, 1 accession SATB2, 146 accessions 10 variants LOC348751, 25 accessions 8 variants ZOOM IN                D:disease,C:conserved,I:interactions,R:regulation,P:publications         Read more...
Annotated mRNA diagrams back to top
Bibliography:               8 articles in PubMed back to top
? Gene Summary Gene on genome mRNA:.a, .b, .c, .d, .e, .f, .g, .h, .i-u, .j-u Alternative mRNAs features, proteins, introns, exons, sequences Expression Tissue Function, regulation, related genes DCI

To mine knowledge about the gene, please click the 'Gene Summary' or the 'Function, regulation, related genes ' tab at the top of the page. The 'Gene Summary' page includes all we learnt about the gene, functional annotations of neighboring genes, maps, links to other sites and the bibliography. The 'Function, regulation, related genes ' page includes Diseases (D), Pathways, GO annotations, conserved domains (C), interactions (I) reference into function, and pointers to all genes with the same functional annotation.
To compare alternative variants, their summarized annotations, predicted proteins, introns and exons, or to access any sequence, click the 'Alternative mRNAs features' tab. To see a specific mRNA variant diagram, sequence and annotation, click the variant name in the 'mRNA' tab. To examine expression data from all cDNAs clustered in this gene by AceView, click the 'Expression tissue'.

If you know more about this gene, or found errors, please share your knowledge. Thank you !