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HomoloGene:56228. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PGAM2,  H.sapiens
phosphoglycerate mutase 2 (muscle)
    NP_000281.2
253 aa
   PGAM2,  P.troglodytes
phosphoglycerate mutase 2 (muscle)
    XP_001143059.1
253 aa
   PGAM2,  M.mulatta
phosphoglycerate mutase 2 (muscle)
    XP_001116220.1
240 aa
   PGAM2,  C.lupus
phosphoglycerate mutase 2 (muscle)
    XP_532718.2
288 aa
   PGAM2,  B.taurus
phosphoglycerate mutase 2 (muscle)
    NP_001033200.1
253 aa
   Pgam2,  M.musculus
phosphoglycerate mutase 2
    NP_061358.1
253 aa
   Pgam2,  R.norvegicus
phosphoglycerate mutase 2 (muscle)
    NP_059024.1
253 aa
   pgam2,  X.tropicalis
phosphoglycerate mutase 2 (muscle)
    NP_001005665.1
253 aa
   pgam2,  D.rerio
phosphoglycerate mutase 2 (muscle)
    NP_957318.1
255 aa
   Pglym87,  D.melanogaster
Pglym87
    NP_652041.2
292 aa
   GPM1,  S.cerevisiae
GPM1
    NP_012770.1
247 aa
   KLLA0E11859g,  K.lactis
KLLA0E11859g
    XP_454486.1
247 aa
   AGOS_ACR056W,  E.gossypii
AGOS_ACR056W
    NP_983459.2
247 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Myopathy due to phosphoglycerate mutase deficiency.



Publications
Articles associated with genes and sequences of this homology group.

Glycolysis supports embryonic muscle growth by promoting myoblast fusion.
Tixier V, et al. Proc Natl Acad Sci U S A 110, 18982-7 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
HP (cl11399)
  Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pgam2 includes H.sapiens PGAM2 and R.norvegicus Pgam2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (15 transcripts, 11 species)
Actinopterygii - bony fishes (12 transcripts, 10 species)
Amphibia - amphibians (4 transcripts, 2 species)

Arthropoda
Insecta - insects (5 transcripts, 4 species)

Platyhelminthes
Trematoda - flatworms (3 transcripts, 2 species)

Streptophyta
Eudicotyledons - eudicots (3 transcripts, 1 species)
Liliopsida - monocots (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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