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HomoloGene:7135. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   EIF6,  H.sapiens
eukaryotic translation initiation factor 6
    NP_001254739.1
245 aa
   EIF6,  P.troglodytes
eukaryotic translation initiation factor 6
    XP_003953760.1
245 aa
   EIF6,  C.lupus
eukaryotic translation initiation factor 6
    XP_534401.2
331 aa
   EIF6,  B.taurus
eukaryotic translation initiation factor 6
    NP_777255.1
245 aa
   Eif6,  M.musculus
eukaryotic translation initiation factor 6
    NP_034709.1
245 aa
   Eif6,  R.norvegicus
eukaryotic translation initiation factor 6
    NP_001032429.1
245 aa
   EIF6,  G.gallus
eukaryotic translation initiation factor 6
    NP_001026019.1
245 aa
   eif6,  X.tropicalis
eukaryotic translation initiation factor 6
    NP_001006884.1
245 aa
   eif6,  D.rerio
eukaryotic translation initiation factor 6
    NP_957238.1
245 aa
   eIF6,  D.melanogaster
eIF6
    NP_659573.1
245 aa
   AgaP_AGAP001380,  A.gambiae
AgaP_AGAP001380
    XP_321758.5
245 aa
   eif-6,  C.elegans
eif-6
    NP_493272.1
246 aa
   TIF6,  S.cerevisiae
TIF6
    NP_015341.1
245 aa
   KLLA0D02046g,  K.lactis
KLLA0D02046g
    XP_453159.1
245 aa
   AGOS_ADL030C,  E.gossypii
AGOS_ADL030C
    NP_984067.1
245 aa
   tif6,  S.pombe
tif6
    NP_588491.1
244 aa
   MGG_01671,  M.oryzae
MGG_01671
    XP_003714657.1
246 aa
   NCU09004,  N.crassa
NCU09004
    XP_959032.1
246 aa
   emb1624,  A.thaliana
emb1624
    NP_191121.1
245 aa
   Os07g0639800,  O.sativa
Os07g0639800
    NP_001060417.1
245 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Identification of ITGB4BP as a new interaction protein of P311.
Peng X, et al. Life Sci 90, 585-90 (2012).
MicroRNA silencing through RISC recruitment of eIF6.
Chendrimada TP, et al. Nature 447, 823-8 (2007).
Formation of nuclear matrix filaments by p27(BBP)/eIF6.
Ceci M, et al. Biochem Biophys Res Commun 295, 295-9 (2002).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
eIF-6 (pfam01912)
  eIF-6 family.
IF6 (cl00241)
  Ribosome anti-association factor IF6 binds the large ribosomal subunit and prevents the two subunits from associating during translation initiation. IF6 comprises a family of translation factors that includes both eukaryotic (eIF6) and archeal (aIF6) ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Eif6 includes H.sapiens EIF6 and R.norvegicus Eif6.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (53 transcripts, 33 species)
Liliopsida - monocots (17 transcripts, 9 species)
Coniferopsida - conifers (6 transcripts, 3 species)
Bryopsida - mosses (2 transcripts, 1 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)

Chlorophyta
Chlorophyceae - green algae (2 transcripts, 2 species)

Chordata
Mammalia - mammals (17 transcripts, 15 species)
Actinopterygii - bony fishes (13 transcripts, 11 species)
Ascidiacea - tunicates (3 transcripts, 1 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (14 transcripts, 12 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (3 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (4 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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