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HomoloGene:20707. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   TRHR,  H.sapiens
thyrotropin-releasing hormone receptor
    NP_003292.1
398 aa
   TRHR,  P.troglodytes
thyrotropin-releasing hormone receptor
    XP_528214.2
398 aa
   TRHR,  M.mulatta
thyrotropin-releasing hormone receptor
    XP_001091307.1
398 aa
   TRHR,  C.lupus
thyrotropin-releasing hormone receptor
    XP_539128.1
398 aa
   TRHR,  B.taurus
thyrotropin-releasing hormone receptor
    NP_776628.1
398 aa
   Trhr,  M.musculus
thyrotropin releasing hormone receptor
    NP_038724.1
393 aa
   Trhr,  R.norvegicus
thyrotropin releasing hormone receptor
    NP_037179.1
412 aa
   TRHR,  G.gallus
thyrotropin-releasing hormone receptor
    NP_990261.1
395 aa
   trhr,  X.tropicalis
thyrotropin-releasing hormone receptor
    XP_002938958.1
397 aa
   LOC569382,  D.rerio
thyrotropin-releasing hormone receptor 1
    NP_001108160.1
399 aa
   trhra,  D.rerio
thyrotropin-releasing hormone receptor a
    XP_687246.3
393 aa
   GPRNPR1,  A.gambiae
GPRNPR1
    XP_312031.5
762 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Thyrotropin-releasing hormone resistance, generalized.



Publications
Articles associated with genes and sequences of this homology group.

Subcellular trafficking of the TRH receptor: effect of phosphorylation.
Jones BW & Hinkle PM. Mol Endocrinol 23, 1466-78 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_4 (cl10458)
  Olfactory receptor.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Trhr includes H.sapiens TRHR and R.norvegicus Trhr.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 6 species)
Actinopterygii - bony fishes (6 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (6 transcripts, 5 species)

 

 

 

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