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HomoloGene:40822. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PRDM2,  H.sapiens
PR domain containing 2, with ZNF domain
    NP_036363.2
1718 aa
   PRDM2,  P.troglodytes
PR domain containing 2, with ZNF domain
    XP_003954505.1
1482 aa
   PRDM2,  M.mulatta
PR domain containing 2, with ZNF domain
    XP_001107002.1
1709 aa
   PRDM2,  C.lupus
PR domain containing 2, with ZNF domain
    XP_005618037.1
1505 aa
   PRDM2,  B.taurus
PR domain containing 2, with ZNF domain
    XP_003587126.2
1624 aa
   Prdm2,  M.musculus
PR domain containing 2, with ZNF domain
    NP_001074824.3
1709 aa
   Prdm2,  R.norvegicus
PR domain containing 2, with ZNF domain
    NP_001071116.1
1706 aa
   PRDM2,  G.gallus
PR domain containing 2, with ZNF domain
    XP_003642562.2
1696 aa
   prdm2,  X.tropicalis
PR domain containing 2, with ZNF domain
    NP_001123857.1
1609 aa
   prdm2b,  D.rerio
PR domain containing 2, with ZNF domain b
    XP_002663834.2
1792 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Anticancer activity of the PR domain of tumor suppressor RIZ1.
Sun W, et al. Int J Med Sci 8, 161-7 (2011).
Suppression of RIZ in biologically unfavourable neuroblastomas.
Geli J, et al. Int J Oncol 37, 1323-30 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ZnF_C2H2 (smart00355)
  zinc finger.
zf-C2H2 (cl15478)
  Zinc finger, C2H2 type.
zf-C2H2_4 (pfam13894)
  C2H2-type zinc finger.
SET (cl02566)
  SET domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Prdm2 includes H.sapiens PRDM2 and R.norvegicus Prdm2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 9 species)
Aves - birds (4 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Actinopterygii - bony fishes (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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