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HomoloGene:2432. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   TGFB2,  H.sapiens
transforming growth factor, beta 2
    NP_001129071.1
442 aa
   TGFB2,  P.troglodytes
transforming growth factor, beta 2
    XP_001172158.1
442 aa
   TGFB2,  M.mulatta
transforming growth factor, beta 2
    XP_001103911.1
442 aa
   TGFB2,  C.lupus
transforming growth factor, beta 2
    XP_545713.2
442 aa
   TGFB2,  B.taurus
transforming growth factor, beta 2
    NP_001106723.1
414 aa
   Tgfb2,  M.musculus
transforming growth factor, beta 2
    NP_033393.2
414 aa
   Tgfb2,  R.norvegicus
transforming growth factor, beta 2
    NP_112393.1
442 aa
   TGFB2,  G.gallus
transforming growth factor, beta 2
    XP_003641018.1
412 aa
   tgfb2,  X.tropicalis
transforming growth factor, beta 2
    XP_002936067.1
411 aa
   tgfb2,  D.rerio
transforming growth factor, beta 2
    NP_919366.1
411 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Transforming growth factor-beta inhibits the expression of clock genes.
Gast H, et al. Ann N Y Acad Sci 1261, 79-87 (2012).
Type II TGFβ receptor modulates chondrocyte phenotype.
Baugé C, et al. Age (Dordr) 35, 1105-16 (2013).
High nephron endowment protects against salt-induced hypertension.
Walker KA, et al. Am J Physiol Renal Physiol 303, F253-8 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TGF_beta (pfam00019)
  Transforming growth factor beta like domain.
TGFb_propeptide (pfam00688)
  TGF-beta propeptide.
TGFb_propeptide (pfam00688)
  TGF-beta propeptide.
TGF_beta (cl02510)
  Transforming growth factor beta like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tgfb2 includes H.sapiens TGFB2 and R.norvegicus Tgfb2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (16 transcripts, 13 species)
Actinopterygii - bony fishes (4 transcripts, 4 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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