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HomoloGene:128645. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CES2,  H.sapiens
carboxylesterase 2
    NP_003860.2
623 aa
   CES2,  P.troglodytes
carboxylesterase 2
    XP_001160359.1
623 aa
   CES2,  C.lupus
carboxylesterase 2
    XP_864764.2
572 aa
   CES2,  B.taurus
carboxylesterase 2
    NP_001029432.1
553 aa
   Ces2h,  M.musculus
carboxylesterase 2H
    NP_001258974.1
558 aa
   Ces2h,  R.norvegicus
carboxylesterase 2H
    NP_001037723.1
558 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Clinical implications of CES2 RNA expression in neuroblastoma.
Uchida K, et al. J Pediatr Surg 48, 502-9 (2013).
Relationship between CES2 genetic variations and rifampicin metabolism.
Song SH, et al. J Antimicrob Chemother 68, 1281-4 (2013).
Functional study of the 830C>G polymorphism of the human carboxylesterase 2 gene.
Bellott R, et al. Cancer Chemother Pharmacol 61, 481-8 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
COesterase (pfam00135)
  Carboxylesterase family.
Aes (COG0657)
  Esterase/lipase [Lipid metabolism].



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ces2h includes H.sapiens CES2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 7 species)
Cephalochordata - lancelets (3 transcripts, 1 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)

Arthropoda
Arachnida - arachnids (5 transcripts, 1 species)
Insecta - insects (4 transcripts, 4 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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