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HomoloGene:20626. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PTPRS,  H.sapiens
protein tyrosine phosphatase, receptor type, S
    NP_002841.3
1948 aa
   PTPRS,  P.troglodytes
protein tyrosine phosphatase, receptor type, S
    XP_003316070.1
1948 aa
   PTPRS,  M.mulatta
protein tyrosine phosphatase, receptor type, S
    XP_001083499.2
1842 aa
   PTPRS,  B.taurus
protein tyrosine phosphatase, receptor type, S
    XP_002688964.1
1948 aa
   Ptprs,  M.musculus
protein tyrosine phosphatase, receptor type, S
    NP_035348.2
1907 aa
   Ptprs,  R.norvegicus
protein tyrosine phosphatase, receptor type, S
    NP_062013.1
1863 aa
   ptprsa,  D.rerio
protein tyrosine phosphatase, receptor type, s, a
    XP_001920953.4
1940 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Identification of PTPsigma as an autophagic phosphatase.
Martin KR, et al. J Cell Sci 124, 812-9 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
I-set (pfam07679)
  Immunoglobulin I-set domain.
PTPc (smart00194)
  Protein tyrosine phosphatase, catalytic domain.
PTPc (cd00047)
  Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
Ig (cl11960)
  Immunoglobulin domain.
I-set (pfam07679)
  Immunoglobulin I-set domain.
FN3 (cl00065)
  Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
Ig (cl11960)
  Immunoglobulin domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ptprs includes H.sapiens PTPRS and R.norvegicus PTPRS.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (21 transcripts, 9 species)
Actinopterygii - bony fishes (19 transcripts, 8 species)
Aves - birds (5 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

 

 

 

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