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HomoloGene:37314. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ALPL,  H.sapiens
alkaline phosphatase, liver/bone/kidney
    NP_000469.3
524 aa
   ALPL,  P.troglodytes
alkaline phosphatase, liver/bone/kidney
    XP_003307915.1
533 aa
   ALPL,  M.mulatta
alkaline phosphatase, liver/bone/kidney
    XP_001109717.2
524 aa
   ALPL,  C.lupus
alkaline phosphatase, liver/bone/kidney
    NP_001184066.1
522 aa
   ALPL,  B.taurus
alkaline phosphatase, liver/bone/kidney
    NP_789828.2
524 aa
   Alpl,  M.musculus
alkaline phosphatase, liver/bone/kidney
    NP_001274101.1
524 aa
   Alpl,  R.norvegicus
alkaline phosphatase, liver/bone/kidney
    NP_037191.1
524 aa
   ALPL,  G.gallus
alkaline phosphatase, liver/bone/kidney
    NP_990691.1
519 aa
   LOC100485467,  X.tropicalis
alkaline phosphatase, tissue-nonspecific isozyme-like
    XP_002943485.2
439 aa
   alp3,  D.rerio
alkaline phosphatase 3
    NP_001265768.1
534 aa
   CG8147,  D.melanogaster
CG8147
    NP_649897.4
546 aa
   AgaP_AGAP001684,  A.gambiae
AgaP_AGAP001684
    XP_321411.3
548 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Odontohypophosphatasia.
Hypophosphatasia, infantile.
Hypophosphatasia, childhood.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
alkPPc (cl19058)
  Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH. ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Alpl includes H.sapiens ALPL and R.norvegicus Alpl.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (17 transcripts, 10 species)
Mammalia - mammals (10 transcripts, 10 species)
Ascidiacea - tunicates (8 transcripts, 3 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (20 transcripts, 10 species)
Arachnida - arachnids (4 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (3 transcripts, 1 species)
Hydrozoa - hydrozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (3 transcripts, 1 species)

Echinodermata
Echinoidea - sea urchins (3 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)
Liliopsida - monocots (1 transcript, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)

 

 

 

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