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HomoloGene:48068. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

FYN,  H.sapiens
FYN oncogene related to SRC, FGR, YES
NP_694592.1
534 aa
FYN,  P.troglodytes
FYN oncogene related to SRC, FGR, YES
XP_001159342.1
537 aa
FYN,  M.mulatta
FYN oncogene related to SRC, FGR, YES
XP_001085015.1
537 aa
FYN,  C.lupus
FYN oncogene related to SRC, FGR, YES
XP_005627774.1
537 aa
FYN,  B.taurus
FYN oncogene related to SRC, FGR, YES
NP_001071440.1
537 aa
Fyn,  M.musculus
Fyn proto-oncogene
NP_032080.2
534 aa
Fyn,  R.norvegicus
FYN oncogene related to SRC, FGR, YES
NP_036887.1
537 aa
FYN,  G.gallus
FYN oncogene related to SRC, FGR, YES
NP_990680.1
534 aa
fyn,  X.tropicalis
FYN oncogene related to SRC, FGR, YES
XP_002936976.2
534 aa
fynb,  D.rerio
FYN oncogene related to SRC, FGR, YES b
NP_001025140.1
544 aa
src-1,  C.elegans
src-1
NP_490866.4
533 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Fyn kinase is required for optimal humoral responses.
Chaimowitz NS, et al. PLoS One 8, e60640 (2013).
In silico study of Alzheimer's disease in relation to FYN gene.
Anbarasu A & Kundu A. Interdiscip Sci 4, 153-60 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
SH2 (cl15255)
  Src homology 2 (SH2) domain.
SH3 (cl17036)
  Src Homology 3 domain superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fyn includes H.sapiens FYN and R.norvegicus Fyn.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (24 transcripts, 10 species)
Mammalia - mammals (18 transcripts, 14 species)
Amphibia - amphibians (4 transcripts, 2 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (4 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Arthropoda
Malacostraca - crustaceans (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

 

 

 

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