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HomoloGene:1324. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CANX,  H.sapiens
calnexin
    NP_001019820.1
592 aa
   CANX,  P.troglodytes
calnexin
    XP_518152.2
592 aa
   CANX,  M.mulatta
calnexin
    XP_002804712.1
627 aa
   CANX,  C.lupus
calnexin
    NP_001003232.1
593 aa
   CANX,  B.taurus
calnexin
    NP_001099082.1
593 aa
   Canx,  M.musculus
calnexin
    NP_001103969.1
591 aa
   Canx,  R.norvegicus
calnexin
    NP_742005.1
591 aa
   CANX,  G.gallus
calnexin
    NP_001025791.2
601 aa
   canx,  X.tropicalis
calnexin
    NP_001005668.1
606 aa
   canx,  D.rerio
calnexin
    NP_998613.1
600 aa
   Cnx99A,  D.melanogaster
Calnexin 99A
    NP_001036767.1
605 aa
   CG1924,  D.melanogaster
CG1924
    NP_572788.2
570 aa
   Cnx14D,  D.melanogaster
Calnexin 14D
    NP_573131.1
639 aa
   AgaP_AGAP005032,  A.gambiae
AgaP_AGAP005032
    XP_313899.4
632 aa
   cnx-1,  C.elegans
cnx-1
    NP_499176.1
619 aa
   AT5G07340,  A.thaliana
AT5G07340
    NP_001190249.1
540 aa
   CNX1,  A.thaliana
CNX1
    NP_200987.1
530 aa
   Os04g0402100,  O.sativa
Os04g0402100
    NP_001052692.1
537 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Calnexin is required for zebrafish posterior lateral line development.
Hung IC, et al. Int J Dev Biol 57, 427-38 (2013).
Role of cysteine amino acid residues in calnexin.
Coe H, et al. Mol Cell Biochem 359, 271-81 (2012).
Calnexin deficiency leads to dysmyelination.
Kraus A, et al. J Biol Chem 285, 18928-38 (2010).
Endoplasmic reticulum stress in the absence of calnexin.
Coe H, et al. Cell Stress Chaperones 13, 497-507 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Calreticulin (pfam00262)
  Calreticulin family.
Calreticulin (pfam00262)
  Calreticulin family.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Canx includes H.sapiens CANX and R.norvegicus Canx.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (63 transcripts, 35 species)
Liliopsida - monocots (16 transcripts, 9 species)
Coniferopsida - conifers (6 transcripts, 3 species)
Bryopsida - mosses (2 transcripts, 1 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (1 transcript, 1 species)

Chordata
Mammalia - mammals (22 transcripts, 16 species)
Actinopterygii - bony fishes (11 transcripts, 8 species)
Aves - birds (6 transcripts, 3 species)
Ascidiacea - tunicates (4 transcripts, 3 species)
Amphibia - amphibians (4 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (3 transcripts, 3 species)
Arachnida - arachnids (3 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (3 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (3 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (2 transcripts, 1 species)
Polychaeta - segmented worms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (6 transcripts, 3 species)
Pezizomycetes - ascomycetes (2 transcripts, 1 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

 

 

 

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