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HomoloGene:2846. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   DLK1,  H.sapiens
delta-like 1 homolog (Drosophila)
    NP_003827.3
383 aa
   DLK1,  P.troglodytes
delta-like 1 homolog (Drosophila)
    XP_003314552.2
383 aa
   DLK1,  M.mulatta
delta-like 1 homolog (Drosophila)
    XP_001106331.1
383 aa
   DLK1,  C.lupus
delta-like 1 homolog (Drosophila)
    XP_547982.4
383 aa
   Dlk1,  M.musculus
delta-like 1 homolog (Drosophila)
    NP_034182.2
385 aa
   Dlk1,  R.norvegicus
delta-like 1 homolog (Drosophila)
    NP_446196.1
383 aa
   DLK1,  G.gallus
delta-like 1 homolog (Drosophila)
    NP_001135726.1
386 aa
   dlk1,  X.tropicalis
delta-like 1 homolog (Drosophila)
    XP_002936624.1
382 aa
   LOC101883341,  D.rerio
protein delta homolog 1-like
    XP_005173621.1
322 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Dlk1 is a negative regulator of emerging hematopoietic stem and progenitor cells.
Mirshekar-Syahkal B, et al. Haematologica 98, 163-71 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
EGF_CA (cl09941)
  Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
EGF_CA (cl09941)
  Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Dlk1 includes H.sapiens DLK1 and R.norvegicus Dlk1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 9 species)
Aves - birds (3 transcripts, 3 species)
Amniota - vertebrates (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (3 transcripts, 1 species)

Arthropoda
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 1 species)

 

 

 

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