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HomoloGene:31015. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ACACA,  H.sapiens
acetyl-CoA carboxylase alpha
    NP_942131.1
2383 aa
   ACACA,  P.troglodytes
acetyl-CoA carboxylase alpha
    XP_511428.3
2383 aa
   ACACA,  M.mulatta
acetyl-CoA carboxylase alpha
    XP_001111823.1
2383 aa
   ACACA,  C.lupus
acetyl-CoA carboxylase alpha
    XP_005624832.1
2383 aa
   ACACA,  B.taurus
acetyl-CoA carboxylase alpha
    NP_776649.1
2346 aa
   Acaca,  M.musculus
acetyl-Coenzyme A carboxylase alpha
    NP_579938.2
2345 aa
   Acaca,  R.norvegicus
acetyl-CoA carboxylase alpha
    NP_071529.1
2345 aa
   ACACA,  G.gallus
acetyl-CoA carboxylase alpha
    NP_990836.1
2324 aa
   acaca,  X.tropicalis
acetyl-CoA carboxylase alpha
    XP_004911956.1
2269 aa
   acaca,  D.rerio
acetyl-Coenzyme A carboxylase alpha
    NP_001258237.1
2390 aa
   ACC,  D.melanogaster
Acetyl-CoA carboxylase
    NP_724636.1
2323 aa
   AgaP_AGAP005175,  A.gambiae
AgaP_AGAP005175
    XP_314071.4
2323 aa
   ACC1,  S.cerevisiae
ACC1
    NP_014413.1
2233 aa
   KLLA0F06072g,  K.lactis
KLLA0F06072g
    XP_455355.1
2231 aa
   AGOS_AAR071W,  E.gossypii
AGOS_AAR071W
    NP_982612.1
2231 aa
   cut6,  S.pombe
cut6
    NP_593271.1
2280 aa
   MGG_07613,  M.oryzae
MGG_07613
    XP_003711534.1
2344 aa
   NCU08535,  N.crassa
NCU08535
    XP_963017.1
2275 aa
   ACC1,  A.thaliana
ACC1
    NP_174849.2
2254 aa
   ACC2,  A.thaliana
ACC2
    NP_174850.4
2355 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Acetyl-CoA carboxylase deficiency.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CPSase_L_chain (pfam00289)
  Carbamoyl-phosphate synthase L chain, N-terminal domain.
Biotin_carb_C (pfam02785)
  Biotin carboxylase C-terminal domain.
ATP-grasp_4 (cl03087)
  ATP-grasp domain.
Carboxyl_trans (pfam01039)
  Carboxyl transferase domain.
ACC_central (pfam08326)
  Acetyl-CoA carboxylase, central region.
ATP-grasp_4 (pfam13535)
  ATP-grasp domain.
ATP-grasp_4 (cl17255)
  ATP-grasp domain.
PRK07189 (cl17682)
  malonate decarboxylase subunit beta; Reviewed.
CPSase_L_chain (pfam00289)
  Carbamoyl-phosphate synthase L chain, N-terminal domain.
Carboxyl_trans (pfam01039)
  Carboxyl transferase domain.
ACC_central (pfam08326)
  Acetyl-CoA carboxylase, central region.
Biotin_carb_C (cl08365)
  Biotin carboxylase C-terminal domain.
Peptidases_S8_S53 (cl10459)
  Peptidase domain in the S8 and S53 families.
Biotinyl_lipoyl_domains (cl11404)
  Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl, ...
ATP-grasp_4 (cl17255)
  ATP-grasp domain.
ACCA (cl19172)
  Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Acaca includes H.sapiens ACACA and R.norvegicus Acaca.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (44 transcripts, 28 species)
Liliopsida - monocots (24 transcripts, 9 species)
Coniferopsida - conifers (4 transcripts, 3 species)
Bryopsida - mosses (2 transcripts, 1 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)

Chordata
Actinopterygii - bony fishes (27 transcripts, 6 species)
Mammalia - mammals (14 transcripts, 10 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (10 transcripts, 7 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (2 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (2 transcripts, 1 species)

 

 

 

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