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HomoloGene:22969. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CENPF,  H.sapiens
centromere protein F, 350/400kDa
    NP_057427.3
3114 aa
   CENPF,  P.troglodytes
centromere protein F, 350/400kDa (mitosin)
    XP_001171564.1
3114 aa
   CENPF,  M.mulatta
centromere protein F, 350/400kDa (mitosin)
    XP_001105956.2
3103 aa
   CENPF,  C.lupus
centromere protein F, 350/400kDa (mitosin)
    XP_003639228.1
3061 aa
   CENPF,  B.taurus
centromere protein F, 350/400kDa (mitosin)
    NP_001243515.1
3079 aa
   Cenpf,  M.musculus
centromere protein F
    NP_001074832.2
2997 aa
   Cenpf,  R.norvegicus
centromere protein F
    NP_001094297.1
2985 aa
   CENPF,  G.gallus
centromere protein F, 350/400kDa (mitosin)
    NP_989976.2
2935 aa
   cenpf,  X.tropicalis
centromere protein F, 350/400kDa
    XP_002934738.2
2609 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Silencing CENPF in bovine preimplantation embryo induces arrest at 8-cell stage.
Toralov√° T, et al. Reproduction 138, 783-91 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Rb-bdg_C_Cenp-F (pfam10490)
  Rb-binding domain of kinetochore protein Cenp-F/LEK1.
Cenp-F_N (pfam10481)
  Cenp-F N-terminal domain.
TMPIT (pfam07851)
  TMPIT-like protein.
Cenp-F_leu_zip (pfam10473)
  Leucine-rich repeats of kinetochore protein Cenp-F/LEK1.
SbcC (COG0419)
  ATPase involved in DNA repair [DNA replication, recombination, and repair].
Smc (COG1196)
  Chromosome segregation ATPases [Cell division and chromosome partitioning].
SMC_prok_B (TIGR02168)
  chromosome segregation protein SMC, common bacterial type.
CENP-F_N (pfam10481)
  Cenp-F N-terminal domain.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cenpf includes H.sapiens CENPF and R.norvegicus Cenpf.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 9 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Aves - birds (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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