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HomoloGene:1612. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   NR4A1,  H.sapiens
nuclear receptor subfamily 4, group A, member 1
    NP_001189162.1
611 aa
   NR4A1,  P.troglodytes
nuclear receptor subfamily 4, group A, member 1
    XP_003313739.1
652 aa
   NR4A1,  M.mulatta
nuclear receptor subfamily 4, group A, member 1
    XP_001085399.2
652 aa
   NR4A1,  C.lupus
nuclear receptor subfamily 4, group A, member 1
    NP_001003227.1
598 aa
   NR4A1,  B.taurus
nuclear receptor subfamily 4, group A, member 1
    NP_001069379.1
598 aa
   Nr4a1,  M.musculus
nuclear receptor subfamily 4, group A, member 1
    NP_034574.1
601 aa
   Nr4a1,  R.norvegicus
nuclear receptor subfamily 4, group A, member 1
    NP_077364.2
597 aa
   nr4a1,  X.tropicalis
nuclear receptor subfamily 4, group A, member 1
    NP_001072303.1
577 aa
   nr4a1,  D.rerio
nuclear receptor subfamily 4, group A, member 1
    NP_001002173.1
574 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Nur77 inhibits androgen-induced bladder cancer growth.
Wu J, et al. Cancer Invest 31, 654-60 (2013).
TR3 modulates platinum resistance in ovarian cancer.
Wilson AJ, et al. Cancer Res 73, 4758-69 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NR_DBD_like (cl02596)
  DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers.
NR_LBD (cl11397)
  The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nr4a1 includes H.sapiens NR4A1 and R.norvegicus Nr4a1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (17 transcripts, 11 species)
Actinopterygii - bony fishes (12 transcripts, 9 species)
Amphibia - amphibians (3 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

 

 

 

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