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HomoloGene:172. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   IL2RG,  H.sapiens
interleukin 2 receptor, gamma
    NP_000197.1
369 aa
   LOC101059843,  P.troglodytes
cytokine receptor common subunit gamma-like
    XP_003954068.1
338 aa
   IL2RG,  M.mulatta
interleukin 2 receptor, gamma
    NP_001030606.1
369 aa
   IL2RG,  C.lupus
interleukin 2 receptor, gamma
    NP_001003201.1
373 aa
   IL2RG,  B.taurus
interleukin 2 receptor, gamma
    NP_776784.1
379 aa
   Il2rg,  M.musculus
interleukin 2 receptor, gamma chain
    NP_038591.1
369 aa
   Il2rg,  R.norvegicus
interleukin 2 receptor, gamma
    NP_543165.1
368 aa
   IL2RG,  G.gallus
interleukin 2 receptor, gamma (severe combined immunodeficiency)
    NP_989858.1
374 aa
   LOC100492995,  X.tropicalis
cytokine receptor common subunit gamma-like
    XP_002934932.1
329 aa
   il2rga,  D.rerio
interleukin 2 receptor, gamma a
    NP_001121743.1
362 aa
   il2rgb,  D.rerio
interleukin 2 receptor, gamma b
    NP_001116522.1
385 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Severe combined immunodeficiency, X-linked.
Combined immunodeficiency, X-linked, moderate.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
IL6Ra-bind (cl12153)
  Interleukin-6 receptor alpha chain, binding.
IL6Ra-bind (pfam09240)
  Interleukin-6 receptor alpha chain, binding.
IL6Ra-bind (pfam09240)
  Interleukin-6 receptor alpha chain, binding.
FN3 (cl00065)
  Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Il2rg includes H.sapiens IL2RG and R.norvegicus Il2rg.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 11 species)
Actinopterygii - bony fishes (3 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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