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HomoloGene:3073. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   SDHA,  H.sapiens
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
    NP_004159.2
664 aa
   SDHA,  P.troglodytes
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
    XP_003310656.1
664 aa
   LOC708018,  M.mulatta
succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial-like
    XP_001094170.2
280 aa
   SDHA,  C.lupus
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
    XP_535807.4
721 aa
   SDHA,  B.taurus
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
    NP_776603.1
665 aa
   Sdha,  M.musculus
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
    NP_075770.1
664 aa
   Sdha,  R.norvegicus
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
    NP_569112.1
656 aa
   SDHA,  G.gallus
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
    NP_001264327.1
665 aa
   sdha,  X.tropicalis
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
    NP_001015989.1
665 aa
   sdha,  D.rerio
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
    NP_957204.1
661 aa
   SdhA,  D.melanogaster
Succinate dehydrogenase A
    NP_725882.1
661 aa
   AgaP_AGAP010429,  A.gambiae
AgaP_AGAP010429
    XP_311518.4
659 aa
   sdha-1,  C.elegans
sdha-1
    NP_509446.1
646 aa
   sdha-2,  C.elegans
sdha-2
    NP_492798.1
640 aa
   SDH1,  S.cerevisiae
SDH1
    NP_012774.1
640 aa
   KLLA0D04444g,  K.lactis
KLLA0D04444g
    XP_453260.1
651 aa
   AGOS_ACR052W,  E.gossypii
AGOS_ACR052W
    NP_983455.2
633 aa
   sdh1,  S.pombe
sdh1
    NP_594319.1
641 aa
   MGG_00168,  M.oryzae
MGG_00168
    XP_003718957.1
646 aa
   NCU08336,  N.crassa
NCU08336
    XP_001728186.1
661 aa
   SDH1-1,  A.thaliana
SDH1-1
    NP_201477.1
634 aa
   Os07g0134800,  O.sativa
Os07g0134800
    NP_001058845.1
630 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Mitochondrial respiratory chain complex II deficiency.
Leigh syndrome.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PRK06175 (PRK06175)
  L-aspartate oxidase; Provisional.
Succ_DH_flav_C (pfam02910)
  Fumarate reductase flavoprotein C-term.
NADB_Rossmann (cl09931)
  Rossmann-fold NAD(P)(+)-binding proteins.
Succ_DH_flav_C (pfam02910)
  Fumarate reductase flavoprotein C-term.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Sdha includes H.sapiens SDHA and R.norvegicus Sdha.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (23 transcripts, 17 species)
Actinopterygii - bony fishes (17 transcripts, 10 species)
Ascidiacea - tunicates (4 transcripts, 3 species)
Aves - birds (4 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (20 transcripts, 11 species)
Arachnida - arachnids (2 transcripts, 2 species)
Maxillopoda - crustaceans (2 transcripts, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (3 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (4 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (3 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (48 transcripts, 31 species)
Liliopsida - monocots (21 transcripts, 9 species)
Coniferopsida - conifers (8 transcripts, 3 species)
Bryopsida - mosses (2 transcripts, 1 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (2 transcripts, 2 species)

Ciliophora
Oligohymenophorea - ciliates (8 transcripts, 2 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (2 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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