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HomoloGene:389. Gene conserved in Amniota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   SELE,  H.sapiens
selectin E
    NP_000441.2
610 aa
   SELE,  P.troglodytes
selectin E
    XP_001137309.1
610 aa
   SELE,  M.mulatta
selectin E
    XP_001094967.1
610 aa
   SELE,  C.lupus
selectin E
    NP_001003310.1
611 aa
   Sele,  M.musculus
selectin, endothelial cell
    NP_035475.1
619 aa
   Sele,  R.norvegicus
selectin E
    NP_620234.1
549 aa
   SELE,  G.gallus
selectin E (endothelial adhesion molecule 1)
    XP_422246.4
538 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Atherosclerosis, susceptibility to.
Blood pressure regulation QTL.
IgA nephropathy, susceptiblity to.



Publications
Articles associated with genes and sequences of this homology group.

E-Selectin S128R gene polymorphism in gastric cancer.
Liarmakopoulos E, et al. Int J Biol Markers 28, 38-42 (2013).
E-selectin deficiency attenuates brain ischemia in mice.
Ma XJ, et al. CNS Neurosci Ther 18, 903-8 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CCP (cl00043)
  SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.
CLECT (cl02432)
  C-type lectin (CTL)/C-type lectin-like (CTLD) domain.
EGF_CA (cl09941)
  Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Sele includes H.sapiens SELE and R.norvegicus Sele.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (5 transcripts, 5 species)

 

 

 

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