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HomoloGene:554. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   AHCY,  H.sapiens
adenosylhomocysteinase
    NP_000678.1
432 aa
   AHCY,  P.troglodytes
adenosylhomocysteinase
    XP_514594.2
432 aa
   AHCY,  M.mulatta
adenosylhomocysteinase
    XP_001089745.1
432 aa
   AHCY,  C.lupus
adenosylhomocysteinase
    XP_534388.2
433 aa
   AHCY,  B.taurus
adenosylhomocysteinase
    NP_001029487.1
432 aa
   Ahcy,  M.musculus
S-adenosylhomocysteine hydrolase
    NP_057870.3
432 aa
   Ahcy,  R.norvegicus
adenosylhomocysteinase
    NP_058897.1
432 aa
   AHCY,  G.gallus
adenosylhomocysteinase
    XP_417331.4
405 aa
   ahcy,  X.tropicalis
adenosylhomocysteinase
    NP_001037894.1
433 aa
   ahcy,  D.rerio
S-adenosylhomocysteine hydrolase
    NP_954688.1
433 aa
   Ahcy13,  D.melanogaster
Adenosylhomocysteinase at 13
    NP_511164.2
432 aa
   SAHH_ANOGA,  A.gambiae
SAHH_ANOGA
    XP_311257.2
432 aa
   ahcy-1,  C.elegans
ahcy-1
    NP_491955.1
437 aa
   SAH1,  S.cerevisiae
SAH1
    NP_010961.3
449 aa
   KLLA0A01199g,  K.lactis
KLLA0A01199g
    XP_451052.1
449 aa
   AGOS_AFR243C,  E.gossypii
AGOS_AFR243C
    NP_985790.1
449 aa
   SPBC8D2.18c,  S.pombe
SPBC8D2.18c
    NP_595580.1
433 aa
   MGG_05155,  M.oryzae
MGG_05155
    XP_003712689.1
449 aa
   NCU07930,  N.crassa
NCU07930
    XP_962446.1
449 aa
   SAHH2,  A.thaliana
SAHH2
    NP_189023.1
485 aa
   MEE58,  A.thaliana
MEE58
    NP_193130.1
485 aa
   Os11g0455500,  O.sativa
Os11g0455500
    NP_001067845.2
515 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase.



Publications
Articles associated with genes and sequences of this homology group.

Crystallization of mouse S-adenosyl-L-homocysteine hydrolase.
Ishihara M, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun 66, 313-5 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PRK05476 (PRK05476)
  S-adenosyl-L-homocysteine hydrolase; Provisional.
FDH_GDH_like (cl17240)
  Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ahcy includes H.sapiens AHCY and R.norvegicus Ahcy.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (80 transcripts, 35 species)
Liliopsida - monocots (23 transcripts, 8 species)
Coniferopsida - conifers (8 transcripts, 3 species)
Bryopsida - mosses (2 transcripts, 1 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)

Chlorophyta
Chlorophyceae - green algae (2 transcripts, 2 species)

Chordata
Mammalia - mammals (19 transcripts, 14 species)
Actinopterygii - bony fishes (11 transcripts, 10 species)
Ascidiacea - tunicates (5 transcripts, 3 species)
Aves - birds (3 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (18 transcripts, 13 species)
Branchiopoda - crustaceans (4 transcripts, 1 species)
Arachnida - arachnids (2 transcripts, 2 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (3 transcripts, 2 species)
Anthozoa - anthozoans (2 transcripts, 1 species)

Nematoda
Chromadorea - nematodes (4 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (3 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (13 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (2 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (2 transcripts, 1 species)
Pythiales - oomycetes (2 transcripts, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (2 transcripts, 1 species)

Ciliophora
Oligohymenophorea - ciliates (2 transcripts, 2 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (2 transcripts, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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