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HomoloGene:3708. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   RAPSN,  H.sapiens
receptor-associated protein of the synapse
    NP_005046.2
412 aa
   RAPSN,  P.troglodytes
receptor-associated protein of the synapse
    XP_001168947.1
412 aa
   RAPSN,  C.lupus
receptor-associated protein of the synapse
    XP_850095.1
412 aa
   RAPSN,  B.taurus
receptor-associated protein of the synapse
    NP_001178350.1
412 aa
   Rapsn,  M.musculus
receptor-associated protein of the synapse
    NP_033049.2
412 aa
   Rapsn,  R.norvegicus
receptor-associated protein of the synapse
    NP_001102054.1
359 aa
   RAPSN,  G.gallus
receptor-associated protein of the synapse
    NP_990428.1
412 aa
   rapsn,  X.tropicalis
receptor-associated protein of the synapse
    NP_001005667.1
412 aa
   rapsn,  D.rerio
receptor-associated protein of the synapse, 43kD
    NP_840090.1
412 aa
   CG1909,  D.melanogaster
CG1909
    NP_726586.1
606 aa
   rpy-1,  C.elegans
rpy-1
    NP_495365.1
596 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Myasthenic syndrome, congenital, associated with acetylcholine receptor deficiency.
Myasthenic syndrome, congenital, associated with facial dysmorphism and acetylcholine receptor deficiency.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Rapsyn_N (pfam10579)
  Rapsyn N-terminal myristoylation and linker region.
TPR_12 (pfam13424)
  Tetratricopeptide repeat.
zf-RING_2 (pfam13639)
  Ring finger domain.
TPR (cd00189)
  Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
TPR (cl02429)
  Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
TPR_12 (pfam13424)
  Tetratricopeptide repeat.
RING (cl17238)
  RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rapsn includes H.sapiens RAPSN and R.norvegicus Rapsn.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 8 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (3 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

 

 

 

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