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HomoloGene:1538. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   FUT4,  H.sapiens
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
    NP_002024.1
530 aa
   FUT4,  P.troglodytes
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
    NP_001008985.2
530 aa
   FUT4,  M.mulatta
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
    XP_001089380.1
531 aa
   LOC100682680,  C.lupus
alpha-(1,3)-fucosyltransferase-like
    XP_003432991.2
362 aa
   FUT4,  B.taurus
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
    NP_777161.1
398 aa
   Fut4,  M.musculus
fucosyltransferase 4
    NP_034372.1
433 aa
   Fut4,  R.norvegicus
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
    NP_071555.3
433 aa
   FUT4,  G.gallus
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
    NP_001026658.1
356 aa
   fut4,  X.tropicalis
alpha3-fucosyltransferase
    NP_001004773.1
363 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

In vitro generation of human cells with cancer stem cell properties.
Scaffidi P & Misteli T. Nat Cell Biol 13, 1051-61 (2011).
CD15-expressing nodular lymphocyte-predominant Hodgkin lymphoma.
Venkataraman G, et al. Histopathology 58, 803-5 (2011).
Overexpression of fucosyltransferase IV in A431 cell line increases cell proliferation.
Yang X, et al. Int J Biochem Cell Biol 39, 1722-30 (2007).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Glyco_transf_10 (pfam00852)
  Glycosyltransferase family 10 (fucosyltransferase).
Glyco_transf_10 (pfam00852)
  Glycosyltransferase family 10 (fucosyltransferase).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fut4 includes H.sapiens FUT4 and R.norvegicus Fut4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 7 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 1 species)

 

 

 

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