Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
HomoloGene:4579. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   TFPI,  H.sapiens
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
    NP_006278.1
304 aa
   TFPI,  P.troglodytes
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
    XP_003949980.1
304 aa
   TFPI,  M.mulatta
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
    XP_001104806.1
304 aa
   TFPI,  B.taurus
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
    NP_001231133.1
304 aa
   Tfpi,  M.musculus
tissue factor pathway inhibitor
    NP_035706.1
306 aa
   Tfpi,  R.norvegicus
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
    NP_058896.1
302 aa
   TFPI,  G.gallus
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
    XP_004942460.1
311 aa
   tfpia,  D.rerio
tissue factor pathway inhibitor a
    NP_878292.1
277 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

TFPI gene variation and ischemic stroke.
Pedersen A, et al. Thromb Res 130, 565-7 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Kunitz_BPTI (pfam00014)
  Kunitz/Bovine pancreatic trypsin inhibitor domain.
KU (cl00101)
  BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tfpi includes H.sapiens TFPI and R.norvegicus Tfpi.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

 

 

 

Write to the Help Desk