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HomoloGene:10741. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   OSM,  H.sapiens
oncostatin M
    NP_065391.1
252 aa
   OSM,  P.troglodytes
oncostatin M
    XP_001136178.1
252 aa
   OSM,  M.mulatta
oncostatin M
    XP_001110148.1
252 aa
   OSM,  C.lupus
oncostatin M
    XP_005636497.1
247 aa
   OSM,  B.taurus
oncostatin M
    NP_783644.3
245 aa
   Osm,  M.musculus
oncostatin M
    NP_001013383.1
263 aa
   Osm,  R.norvegicus
oncostatin M
    NP_001006962.1
239 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Oncostatin M is a growth factor for Ewing sarcoma.
David E, et al. Am J Pathol 181, 1782-95 (2012).
Endothelium-derived GM-CSF influences expression of oncostatin M.
Elbjeirami WM, et al. Am J Physiol Cell Physiol 301, C947-53 (2011).
Oncostatin M regulates neural precursor activity in the adult brain.
Beatus P, et al. Dev Neurobiol 71, 619-33 (2011).
Direct anti-cancer effect of oncostatin M on chondrosarcoma.
David E, et al. Int J Cancer 128, 1822-35 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
LIF_OSM (cl02454)
  LIF / OSM family.
LIF_OSM (cl17692)
  LIF / OSM family.
LIF_OSM (cl17692)
  OSM, Oncostatin M



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Osm includes H.sapiens OSM and R.norvegicus Osm.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (5 transcripts, 5 species)

 

 

 

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