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HomoloGene:20099. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   MYL3,  H.sapiens
myosin, light chain 3, alkali; ventricular, skeletal, slow
    NP_000249.1
195 aa
   LOC460327,  P.troglodytes
calmodulin-related protein-like
    XP_003309811.2
318 aa
   MYL3,  M.mulatta
myosin, light chain 3, alkali; ventricular, skeletal, slow
    XP_001113910.1
196 aa
   MYL3,  C.lupus
myosin, light chain 3, alkali; ventricular, skeletal, slow
    XP_005632679.1
201 aa
   MYL3,  B.taurus
myosin, light chain 3, alkali; ventricular, skeletal, slow
    NP_001069969.2
199 aa
   Myl3,  M.musculus
myosin, light polypeptide 3
    NP_034989.1
204 aa
   Myl3,  R.norvegicus
myosin, light chain 3, alkali; ventricular, skeletal, slow
    NP_036738.1
200 aa
   MYL3,  G.gallus
myosin, light chain 3, alkali; ventricular, skeletal, slow
    NP_990490.1
194 aa
   myl3,  X.tropicalis
myosin, light chain 3, alkali; ventricular, skeletal, slow
    NP_989012.1
188 aa
   zgc:66286,  D.rerio
zgc:66286
    NP_956810.1
186 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Cardiomyopathy, familial hypertrophic, 8.



Publications
Articles associated with genes and sequences of this homology group.

Modulation of muscle contraction by a cell-permeable peptide.
T√ľnnemann G, et al. J Mol Med (Berl) 85, 1405-12 (2007).
The functional domains of human ventricular myosin light chain 1.
Xie B, et al. Biophys Chem 106, 57-66 (2003).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
EFh (cd00051)
  EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Myl3 includes H.sapiens MYL3 and R.norvegicus Myl3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 11 species)
Actinopterygii - bony fishes (8 transcripts, 7 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

 

 

 

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