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HomoloGene:20665. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   SLC22A1,  H.sapiens
solute carrier family 22 (organic cation transporter), member 1
    NP_003048.1
554 aa
   SLC22A1,  P.troglodytes
solute carrier family 22 (organic cation transporter), member 1
    XP_001151564.2
582 aa
   LOC703449,  M.mulatta
solute carrier family 22 member 1-like
    XP_001099030.2
647 aa
   SLC22A1,  C.lupus
solute carrier family 22 (organic cation transporter), member 1
    XP_005615754.1
506 aa
   SLC22A1,  B.taurus
solute carrier family 22 (organic cation transporter), member 1
    NP_001094568.1
563 aa
   Slc22a1,  M.musculus
solute carrier family 22 (organic cation transporter), member 1
    NP_033228.2
556 aa
   Slc22a1,  R.norvegicus
solute carrier family 22 (organic cation transporter), member 1
    NP_036829.1
556 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

OCT1 genetic variants influence the pharmacokinetics of morphine in children.
Fukuda T, et al. Pharmacogenomics 14, 1141-51 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MFS (cd06174)
  The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
DUF3099 (pfam11298)
  Protein of unknown function (DUF3099).
2A0119 (TIGR00898)
  cation transport protein.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Slc22a1 includes H.sapiens SLC22A1 and R.norvegicus Slc22a1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 8 species)

 

 

 

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