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HomoloGene:128623. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CYP4F2,  H.sapiens
cytochrome P450, family 4, subfamily F, polypeptide 2
    NP_001073.3
520 aa
   LOC748531,  P.troglodytes
leukotriene-B(4) omega-hydroxylase 2-like
    XP_001172535.2
520 aa
   LOC719317,  M.mulatta
leukotriene-B(4) omega-hydroxylase 1-like
    XP_002808225.1
494 aa
   CYP4F2,  B.taurus
cytochrome P450, family 4, subfamily F, polypeptide 2
    NP_001030214.1
524 aa
   LOC509506,  B.taurus
cytochrome P450, family 4, subfamily F, polypeptide 2-like
    XP_002688601.1
523 aa
   LOC100295883,  B.taurus
cytochrome P450, family 4, subfamily F, polypeptide 2-like
    XP_005208624.1
539 aa
   Cyp4f18,  M.musculus
cytochrome P450, family 4, subfamily f, polypeptide 18
    NP_077764.2
524 aa
   Cyp4f18,  R.norvegicus
cytochrome P450, family 4, subfamily f, polypeptide 18
    NP_001028858.1
524 aa
   cyp4f3,  D.rerio
cytochrome P450, family 4, subfamily F, polypeptide 3
    NP_001083010.1
511 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

The functional variant V433M of the CYP4F2 and the metabolic syndrome in Swedes.
Fava C, et al. Prostaglandins Other Lipid Mediat 98, 31-6 (2012).
Influence of CYP4F2 rs2108622 (V433M) on warfarin dose requirement in Asian patients.
Singh O, et al. Drug Metab Pharmacokinet 26, 130-6 (2011).
CYP4F2 gene V433M polymorphism is associated with ischemic stroke in the male Northern Chinese Han population.
Deng S, et al. Prog Neuropsychopharmacol Biol Psychiatry 34, 664-8 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
p450 (pfam00067)
  Cytochrome P450.
p450 (cl12078)
  Cytochrome P450.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cyp4f18 includes H.sapiens CYP4F2 and R.norvegicus Cyp4f18.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (15 transcripts, 11 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Amphibia - amphibians (2 transcripts, 1 species)
Aves - birds (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Arachnida - arachnids (1 transcript, 1 species)

 

 

 

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