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HomoloGene:3391. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

TGM2,  H.sapiens
transglutaminase 2
NP_004604.2
687 aa
TGM2,  P.troglodytes
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
XP_001144553.2
687 aa
TGM2,  C.lupus
transglutaminase 2
XP_542991.4
687 aa
TGM2,  B.taurus
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
NP_803473.1
687 aa
Tgm2,  M.musculus
transglutaminase 2, C polypeptide
NP_033399.1
686 aa
Tgm2,  R.norvegicus
transglutaminase 2, C polypeptide
NP_062259.2
686 aa
TGM2,  G.gallus
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
NP_990779.1
698 aa
tgm2,  X.tropicalis
transglutaminase 2
NP_001123852.1
691 aa
tgm2b,  D.rerio
transglutaminase 2b
NP_997821.2
679 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Glucose homeostasis in mice is transglutaminase 2 independent.
Iismaa SE, et al. PLoS One 8, e63346 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Transglut_N (pfam00868)
  Transglutaminase family.
Transglut_C (pfam00927)
  Transglutaminase family, C-terminal ig like domain.
Transglut_N (pfam00868)
  Transglutaminase family.
Transglut_C (pfam00927)
  Transglutaminase family, C-terminal ig like domain.
Transglut_core (cl17362)
  Transglutaminase-like superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tgm2 includes H.sapiens TGM2 and R.norvegicus Tgm2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 11 species)
Actinopterygii - bony fishes (7 transcripts, 7 species)
Amphibia - amphibians (4 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 1 species)

 

 

 

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