Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
HomoloGene:743. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PTGS1,  H.sapiens
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
    NP_000953.2
599 aa
   PTGS1,  P.troglodytes
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
    XP_520238.2
574 aa
   PTGS1,  M.mulatta
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
    XP_001088157.1
632 aa
   PTGS1,  C.lupus
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
    NP_001003023.1
633 aa
   PTGS1,  B.taurus
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
    NP_001098793.1
600 aa
   Ptgs1,  M.musculus
prostaglandin-endoperoxide synthase 1
    NP_032995.1
602 aa
   Ptgs1,  R.norvegicus
prostaglandin-endoperoxide synthase 1
    NP_058739.3
602 aa
   PTGS1,  G.gallus
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
    XP_425326.4
607 aa
   ptgs1,  X.tropicalis
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
    NP_001258184.1
588 aa
   ptgs1,  D.rerio
prostaglandin-endoperoxide synthase 1
    NP_705942.1
597 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Cyclooxygenase-1 inhibition attenuates angiotensin II-salt hypertension and neurogenic pressor activity in the rat.
Asirvatham-Jeyaraj N, et al. Am J Physiol Heart Circ Physiol 305, H1462-70 (2013).
[Cyclooxigenase-1 gene polymorphism and aspirin resistance].
Bondar' TN & Kravchenko NA. Tsitol Genet 46, 66-72 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
EGF_CA (cl09941)
  Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
An_peroxidase_like (cl14561)
  Animal heme peroxidases and related proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ptgs1 includes H.sapiens PTGS1 and R.norvegicus Ptgs1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 13 species)
Actinopterygii - bony fishes (13 transcripts, 9 species)
Amphibia - amphibians (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

 

 

 

Write to the Help Desk