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HomoloGene:1763. Gene conserved in Amniota Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   TACSTD2,  H.sapiens
tumor-associated calcium signal transducer 2
323 aa
   TACSTD2,  P.troglodytes
tumor-associated calcium signal transducer 2
324 aa
   LOC716334,  M.mulatta
tumor-associated calcium signal transducer 2-like
323 aa
   TACSTD2,  C.lupus
tumor-associated calcium signal transducer 2
330 aa
   TACSTD2,  B.taurus
tumor-associated calcium signal transducer 2
319 aa
   Tacstd2,  M.musculus
tumor-associated calcium signal transducer 2
317 aa
   Tacstd2,  R.norvegicus
tumor-associated calcium signal transducer 2
317 aa
   TACSTD2,  G.gallus
tumor-associated calcium signal transducer 2
301 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Phenotypic information for the genes in this entry imported from model organism databases.

Corneal dystrophy, gelatinous drop-like.

Articles associated with genes and sequences of this homology group.

Gelatinous drop-like corneal dystrophy.
Tsujikawa M. Cornea 31 Suppl 1, S37-40 (2012).
The Trop-2 signalling network in cancer growth.
Guerra E, et al. Oncogene 32, 1594-600 (2013).
Upregulation of Trop-2 quantitatively stimulates human cancer growth.
Trerotola M, et al. Oncogene 32, 222-33 (2013).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PBP2_LTTR_substrate (cl11398)
  The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily.
TY (cl00150)
  Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tacstd2 includes H.sapiens TACSTD2 and R.norvegicus Tacstd2.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (8 transcripts, 8 species)
Amniota - vertebrates (1 transcript, 1 species)
Actinopterygii - bony fishes (1 transcript, 1 species)




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