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HomoloGene:3279. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   DPP4,  H.sapiens
dipeptidyl-peptidase 4
    NP_001926.2
766 aa
   DPP4,  P.troglodytes
dipeptidyl-peptidase 4
    XP_515858.2
766 aa
   DPP4,  M.mulatta
dipeptidyl-peptidase 4
    NP_001034279.1
766 aa
   DPP4,  C.lupus
dipeptidyl-peptidase 4
    XP_535933.3
755 aa
   Dpp4,  M.musculus
dipeptidylpeptidase 4
    NP_034204.1
760 aa
   Dpp4,  R.norvegicus
dipeptidylpeptidase 4
    NP_036921.1
767 aa
   DPP4,  G.gallus
dipeptidyl-peptidase 4
    NP_001026426.1
759 aa
   dpp4,  X.tropicalis
dipeptidyl-peptidase 4
    NP_001016233.1
751 aa
   fap,  D.rerio
fibroblast activation protein, alpha
    XP_001920834.4
750 aa
   dpp4,  D.rerio
dipeptidyl-peptidase 4
    NP_001154809.1
742 aa
   CG11034,  D.melanogaster
CG11034
    NP_608961.2
751 aa
   AgaP_AGAP008176,  A.gambiae
AgaP_AGAP008176
    XP_317288.4
753 aa
   dpf-2,  C.elegans
dpf-2
    NP_510461.1
829 aa
   DAP2,  S.cerevisiae
DAP2
    NP_011893.1
818 aa
   KLLA0E11485g,  K.lactis
KLLA0E11485g
    XP_454468.1
829 aa
   AGOS_ACR073C,  E.gossypii
AGOS_ACR073C
    NP_983475.2
872 aa
   SPACUNK4.08,  S.pombe
SPACUNK4.08
    NP_593970.1
793 aa
   MGG_07745,  M.oryzae
MGG_07745
    XP_003712956.1
938 aa
   NCU02515,  N.crassa
NCU02515
    XP_965646.1
895 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Dipeptidyl peptidase IV and mortality after an acute heart failure episode.
Lourenço P, et al. J Cardiovasc Pharmacol 62, 138-42 (2013).
CD26 inhibition enhances perfusion recovery in ApoE-/-mice.
Haverslag RT, et al. Curr Vasc Pharmacol 11, 21-8 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Peptidase_S9 (pfam00326)
  Prolyl oligopeptidase family.
DPPIV_N (pfam00930)
  Dipeptidyl peptidase IV (DPP IV) N-terminal region.
DPPIV_N (pfam00930)
  Dipeptidyl peptidase IV (DPP IV) N-terminal region.
Peptidase_S9 (cl19144)
  Prolyl oligopeptidase family.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Dpp4 includes H.sapiens DPP4 and R.norvegicus Dpp4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (13 transcripts, 9 species)
Mammalia - mammals (12 transcripts, 12 species)
Ascidiacea - tunicates (3 transcripts, 3 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (12 transcripts, 8 species)
Maxillopoda - crustaceans (2 transcripts, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

 

 

 

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