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HomoloGene:129927. Gene conserved in Amniota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   HLA-DPB1,  H.sapiens
major histocompatibility complex, class II, DP beta 1
    NP_002112.3
258 aa
   PATR-DPB1,  P.troglodytes
major histocompatibility complex, class II, DP beta 1
    XP_518391.3
258 aa
   MAMU-DPB,  M.mulatta
major histocompatibility complex, class II, DP beta
    NP_001127765.1
258 aa
   BLB3,  G.gallus
Major histocompatibility complex class II beta chain BLB3, (similar to HLA class II, D beta chain)
    XP_423039.4
231 aa
   BLB2,  G.gallus
Major histocompatibility complex class II beta chain BLB2, (similar to HLA class II, D beta chain)
    XP_004945723.1
207 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Beryllium disease, chronic, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

Chronic beryllium disease, HLA-DPB1, and the DP peptide binding groove.
Silveira LJ, et al. J Immunol 189, 4014-23 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MHC_II_beta (pfam00969)
  Class II histocompatibility antigen, beta domain.
MHC_II_beta (cl03042)
  Class II histocompatibility antigen, beta domain.
Ig (cl11960)
  Immunoglobulin domain.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 4 species)

 

 

 

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