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HomoloGene:129541. Gene conserved in Boreoeutheria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   HAVCR2,  H.sapiens
hepatitis A virus cellular receptor 2
301 aa
   HAVCR2,  P.troglodytes
hepatitis A virus cellular receptor 2
301 aa
   HAVCR2,  C.lupus
hepatitis A virus cellular receptor 2
279 aa
   HAVCR2,  B.taurus
hepatitis A virus cellular receptor 2
280 aa
   Havcr2,  M.musculus
hepatitis A virus cellular receptor 2
281 aa
   Havcr2,  R.norvegicus
hepatitis A virus cellular receptor 2
282 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

The expression of Tim-3 in peripheral blood of ovarian cancer.
Wu J, et al. DNA Cell Biol 32, 648-53 (2013).
T-cell immunoglobulin and mucin domain 3 acts as a negative regulator of atherosclerosis.
Foks AC, et al. Arterioscler Thromb Vasc Biol 33, 2558-65 (2013).
Prognostic value of T cell immunoglobulin mucin-3 in prostate cancer.
Piao YR, et al. Asian Pac J Cancer Prev 14, 3897-901 (2013).
A novel soluble form of Tim-3 associated with severe graft-versus-host disease.
Hansen JA, et al. Biol Blood Marrow Transplant 19, 1323-30 (2013).
Tim-3 expression defines regulatory T cells in human tumors.
Yan J, et al. PLoS One 8, e58006 (2013).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
IG_like (smart00410)
  Immunoglobulin like.
V-set (pfam07686)
  Immunoglobulin V-set domain.
Ig (cl11960)
  Immunoglobulin domain.
Ig (cl11960)
  Immunoglobulin domain.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Havcr2 includes H.sapiens HAVCR2 and R.norvegicus Havcr2.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (4 transcripts, 4 species)




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