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HomoloGene:68394. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CTNNA2,  H.sapiens
catenin (cadherin-associated protein), alpha 2
    NP_001269526.1
953 aa
   CTNNA2,  P.troglodytes
catenin (cadherin-associated protein), alpha 2
    XP_003309122.1
860 aa
   CTNNA2,  M.mulatta
catenin (cadherin-associated protein), alpha 2
    XP_001112948.1
953 aa
   CTNNA2,  C.lupus
catenin (cadherin-associated protein), alpha 2
    XP_005630556.1
970 aa
   Ctnna2,  M.musculus
catenin (cadherin associated protein), alpha 2
    NP_001103234.1
953 aa
   Ctnna2,  R.norvegicus
catenin (cadherin associated protein), alpha 2
    NP_001100068.1
953 aa
   CTNNA2,  G.gallus
catenin (cadherin-associated protein), alpha 2
    NP_990467.1
906 aa
   ctnna2,  X.tropicalis
catenin (cadherin-associated protein), alpha 2
    NP_001090774.1
966 aa
   ctnna2,  D.rerio
catenin (cadherin-associated protein), alpha 2
    NP_001152844.1
865 aa
   alpha-Cat,  D.melanogaster
alpha Catenin
    NP_524219.1
917 aa
   AgaP_AGAP003424,  A.gambiae
AgaP_AGAP003424
    XP_311710.4
909 aa
   hmp-1,  C.elegans
hmp-1
    NP_001122991.1
930 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

In vitro and in vivo reconstitution of the cadherin-catenin-actin complex from Caenorhabditis elegans.
Kwiatkowski AV, et al. Proc Natl Acad Sci U S A 107, 14591-6 (2010).
Regulation of a novel alphaN-catenin splice variant in schizophrenic smokers.
Mexal S, et al. Am J Med Genet B Neuropsychiatr Genet 147B, 759-68 (2008).
Monomeric α-catenin links cadherin to the actin cytoskeleton.
Desai R, et al. Nat Cell Biol 15, 261-73 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Vinculin (pfam01044)
  Vinculin family.
Vinculin (pfam01044)
  Vinculin family.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ctnna2 includes H.sapiens CTNNA2 and R.norvegicus Ctnna2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (18 transcripts, 12 species)
Actinopterygii - bony fishes (12 transcripts, 6 species)
Amniota - vertebrates (2 transcripts, 1 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (12 transcripts, 11 species)
Arachnida - arachnids (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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