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HomoloGene:513. Gene conserved in Amniota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CD4,  H.sapiens
CD4 molecule
    NP_000607.1
458 aa
   CD4,  P.troglodytes
CD4 molecule
    NP_001009043.1
458 aa
   CD4,  M.mulatta
CD4 molecule
    NP_001036127.1
458 aa
   CD4,  C.lupus
CD4 molecule
    NP_001003252.1
463 aa
   CD4,  B.taurus
CD4 molecule
    NP_001096695.1
395 aa
   Cd4,  M.musculus
CD4 antigen
    NP_038516.1
457 aa
   Cd4,  R.norvegicus
Cd4 molecule
    NP_036837.1
457 aa
   CD4,  G.gallus
CD4 molecule
    NP_989980.1
487 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
CD4+ lymphocyte deficiency.
Lupus erythematosus, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

Control of inflammatory heart disease by CD4+ T cells.
Barin JG & Čiháková D. Ann N Y Acad Sci 1285, 80-96 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Tcell_CD4_Cterm (pfam12104)
  T cell CD4 receptor C terminal region.
Ig (cl11960)
  Immunoglobulin domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cd4 includes H.sapiens CD4 and R.norvegicus Cd4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 9 species)
Aves - birds (2 transcripts, 2 species)

 

 

 

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