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HomoloGene:3180. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   RHOH,  H.sapiens
ras homolog family member H
191 aa
   RHOH,  P.troglodytes
ras homolog family member H
191 aa
   RHOH,  M.mulatta
ras homolog family member H
191 aa
   RHOH,  C.lupus
ras homolog family member H
191 aa
   RHOH,  B.taurus
ras homolog gene family, member H
191 aa
   Rhoh,  M.musculus
ras homolog gene family, member H
191 aa
   Rhoh,  R.norvegicus
ras homolog family member H
191 aa
   RHOH,  G.gallus
ras homolog family member H
191 aa
   rhoh,  X.tropicalis
ras homolog family member H
190 aa
   rhoh,  D.rerio
ras homolog gene family, member H
195 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

RhoH modulates pre-TCR and TCR signalling by regulating LCK.
Wang H, et al. Cell Signal 23, 249-58 (2011).
Aberrant somatic hypermutations in thyroid lymphomas.
Takakuwa T, et al. Leuk Res 33, 649-54 (2009).
Underexpression of RhoH in Hairy Cell Leukemia.
Galiègue-Zouitina S, et al. Cancer Res 68, 4531-40 (2008).
Multiple Rho proteins regulate the subcellular targeting of PAK5.
Wu X & Frost JA. Biochem Biophys Res Commun 351, 328-35 (2006).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ras_like_GTPase (cl17170)
  Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases).

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rhoh includes H.sapiens RHOH and R.norvegicus Rhoh.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (14 transcripts, 12 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Amphibia - amphibians (1 transcript, 1 species)




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