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HomoloGene:21853. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   TMLHE,  H.sapiens
trimethyllysine hydroxylase, epsilon
    NP_060666.1
421 aa
   TMLHE,  P.troglodytes
trimethyllysine hydroxylase, epsilon
    XP_521349.3
213 aa
   TMLHE,  M.mulatta
trimethyllysine hydroxylase, epsilon
    XP_001099674.1
421 aa
   TMLHE,  C.lupus
trimethyllysine hydroxylase, epsilon
    XP_853649.1
421 aa
   TMLHE,  B.taurus
trimethyllysine hydroxylase, epsilon
    NP_001069532.1
421 aa
   Tmlhe,  M.musculus
trimethyllysine hydroxylase, epsilon
    NP_620097.1
421 aa
   Tmlhe,  R.norvegicus
trimethyllysine hydroxylase, epsilon
    NP_596878.2
433 aa
   TMLHE,  G.gallus
trimethyllysine hydroxylase, epsilon
    NP_001012593.1
418 aa
   tmlhe,  X.tropicalis
trimethyllysine hydroxylase, epsilon
    NP_001096300.1
421 aa
   tmlhe,  D.rerio
trimethyllysine hydroxylase, epsilon
    XP_682831.3
410 aa
   CG4335,  D.melanogaster
CG4335
    NP_650886.1
364 aa
   AgaP_AGAP005447,  A.gambiae
AgaP_AGAP005447
    XP_315450.4
385 aa
   gbh-2,  C.elegans
gbh-2
    NP_495793.2
409 aa
   KLLA0A10945g,  K.lactis
KLLA0A10945g
    XP_451476.1
401 aa
   AGOS_AEL035W,  E.gossypii
AGOS_AEL035W
    NP_984826.2
412 aa
   MGG_07454,  M.oryzae
MGG_07454
    XP_003711352.1
466 aa
   NCU03802,  N.crassa
NCU03802
    XP_961191.2
527 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
???.



Publications
Articles associated with genes and sequences of this homology group.

A common X-linked inborn error of carnitine biosynthesis may be a risk factor for nondysmorphic autism.
Celestino-Soper PB, et al. Proc Natl Acad Sci U S A 109, 7974-81 (2012).
Drosophila HNF4 regulates lipid mobilization and beta-oxidation.
Palanker L, et al. Cell Metab 9, 228-39 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
carnitine_TMLD (TIGR02410)
  trimethyllysine dioxygenase.
DUF971 (cl01414)
  Protein of unknown function (DUF971).
CAS_like (cl00184)
  Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases ...
DUF971 (cl01414)
  Protein of unknown function (DUF971).
ClpB_D2-small (cl11083)
  C-terminal, D2-small domain, of ClpB protein.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tmlhe includes H.sapiens TMLHE and R.norvegicus Tmlhe.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (10 transcripts, 6 species)
Mammalia - mammals (8 transcripts, 8 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (4 transcripts, 4 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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