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HomoloGene:113707. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   BIN1,  H.sapiens
bridging integrator 1
    NP_647593.1
593 aa
   BIN1,  P.troglodytes
bridging integrator 1
    XP_001136718.2
597 aa
   BIN1,  C.lupus
bridging integrator 1
    XP_005631944.1
627 aa
   Bin1,  M.musculus
bridging integrator 1
    NP_033798.1
588 aa
   Bin1,  R.norvegicus
bridging integrator 1
    NP_446411.1
588 aa
   BIN1,  G.gallus
bridging integrator 1
    NP_001006524.2
442 aa
   bin1,  X.tropicalis
bridging integrator 1
    NP_989231.1
508 aa
   LOC563561,  D.rerio
myc box-dependent-interacting protein 1-like
    XP_001921434.4
599 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Myopathy, centronuclear, autosomal recessive.



Publications
Articles associated with genes and sequences of this homology group.

Identification of a novel effector domain of BIN1 for cancer suppression.
Lundgaard GL, et al. J Cell Biochem 112, 2992-3001 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.
SH3 (cl17036)
  Src Homology 3 domain superfamily.
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.
SH3 (cl17036)
  Src Homology 3 domain superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Bin1 includes H.sapiens BIN1 and R.norvegicus Bin1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (15 transcripts, 10 species)
Amphibia - amphibians (6 transcripts, 2 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

 

 

 

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