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HomoloGene:1476. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   EDN1,  H.sapiens
endothelin 1
    NP_001161791.1
211 aa
   EDN1,  P.troglodytes
endothelin 1
    XP_518241.2
212 aa
   EDN1,  M.mulatta
endothelin 1
    XP_001089874.1
211 aa
   EDN1,  C.lupus
endothelin 1
    NP_001002956.1
202 aa
   EDN1,  B.taurus
endothelin 1
    NP_851353.1
202 aa
   Edn1,  M.musculus
endothelin 1
    NP_034234.1
202 aa
   Edn1,  R.norvegicus
endothelin 1
    NP_036680.1
202 aa
   EDN1,  G.gallus
endothelin 1
    XP_418943.2
205 aa
   edn1,  X.tropicalis
endothelin 1
    XP_002932710.1
222 aa
   edn1,  D.rerio
endothelin 1
    NP_571594.1
188 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
High density lipoprotein cholesterol level QTL 7.



Publications
Articles associated with genes and sequences of this homology group.

Immunohistochemical expression of endothelin protein in oral squamous cell carcinoma.
Alaizari NA, et al. Indian J Pathol Microbiol 56, 151-4 (2013).
Endothelin-1 gene polymorphism in sudden sensorineural hearing loss.
Uchida Y, et al. Laryngoscope 123, E59-65 (2013).
Plasma endothelin-1 levels in pancreatic inflammations.
Milnerowicz S, et al. Adv Clin Exp Med 22, 361-8 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Endothelin (pfam00322)
  Endothelin family.
PHA02659 (PHA02659)
  endothelin precursor; Provisional.
END (smart00272)
  Endothelin.
Endothelin (cl15291)
  Endothelin family.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Edn1 includes H.sapiens EDN1 and R.norvegicus Edn1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 10 species)
Actinopterygii - bony fishes (4 transcripts, 3 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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